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It's OK to stop taking AIDS meds: LOTTI Study

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    Greetings, good evening. This is my second youtube video.
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    Tonight i'm wanting to talk a little bit about a study I recently read.
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    As I mentioned in my
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    other video and
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    blogs I quit my AIDS drugs about six years ago,
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    so i find reports like this of great interest.
    The study is called LOTTI
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    and that's L-O-T-T-I,
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    stands for LOng-Term Treatment Interruption.
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    The study recently reported that those of us who have had success with treatment interuptions,
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    or "vacations"
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    might not be all that unusual
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    There are two groups in the study which was done in Italy.
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    They were all
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    patients taking
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    HAART, Highly Active Antiretroviral Therapy
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    or the "AIDS cocktails"
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    and one group took the drugs continuously—that was one arm—the second arm
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    took vacations, or interrupted their therapy,
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    based on CD4 counts.
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    The counts used in this study
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    were 700...
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    at 700 CD4 count
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    patients on the STI (structured treatment interruption) arm could
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    quit their drugs until their CD4 count dropped to
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    350 or lower, at which time they
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    would restart
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    their drug treatment.
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    What was really cool about this study is that
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    over a fourth of the
    0:01:32.440,0:01:34.870
    patients in the STI arm,
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    when they
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    quit their drugs, they never had to restart,
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    which has been my strategy since I quit the drugs six years ago.
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    Though i would use a little bit different numbers for the CD4 counts,perhaps.
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    The study
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    really offers hope to people who are either taking, or facing
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    the choice of taking antiretroviral drugs
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    because of their concern for long-term effects or perhaps they are experiencing illness
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    because of the toxicities.
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    There really are no good reasons
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    for HAART patientsto stay on the drugs continuously
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    and indefinitely and there are several advantages
    to stopping them.
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    There is reduced toxicity
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    There were more cardiologicalproblems due to the effects of drug toxicity
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    in the continuous arm
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    than there were in the STI arm.
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    And these problems
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    are well-known. The modern clinical practice is to simply prescribed
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    even more
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    drugs
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    to deal with the effects.
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    The other
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    known affect of
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    continuous
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    HAART drug use includes disfiguring body effects
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    like lipdystrophy,
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    liver disease, bone problems, and aberrant blood levels
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    with lipids, enzymes and hormones.
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    The big boogie man most frequently used to try to discourage
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    patients from interrupting their HAART treatment
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    is drug resistance.
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    The LOTTI study
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    found that
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    drug resistance was higher in the continuous group.
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    than it was in the STI group.
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    In other words, being
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    off the drugs didn't cause resistence, but being on them did.
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    There is only one patient in the STI arm who developed resistance
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    and that was while they were taking the drug, supposedly after achieving viral suppression.
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    So this really contradicts the
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    common wisdom that's usually heard
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    in the doctor's offices.
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    CD4counts.
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    While about the same number of patients in each arm reached one of the so-called primary endpoints,
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    which in this study
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    was defined as death or disease those in the contiuous arm had a mean CD4 count of
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    891, almost 900,
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    compared to 557 in the STI arm.o
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    So, having higher
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    level of CD4 counts, in this study at any rate,
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    did not result in lowering
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    either death or disease. So much for the
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    protective power of high CD4 counts.
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    The daily drug costs...
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    treatment cost for patients on the STI arm
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    was less than half that of the continuous drug group.
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    Now, cost alone should never be
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    the determining factor in treatment choices,
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    but there never seems to be enough money
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    to fuel the AIDS machine, so
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    this is an important finding too.
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    The other study that's or
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    pretty widely quoted when
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    drug vacations or structured treatment
    interruptions are
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    mentioned,
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    is the SMART study, which was funded
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    by the U.S. National Institute of Allergy and Infectious Diseases (NIAID).
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    This was an international study with over 5400 patients
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    in 33 countries. The study was terminated early
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    because supposedly of too many deaths and adverse affects. What's really strange
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    about this study is that
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    79 of those 85 deaths
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    occurred in the U.S.
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    even those only 55% of the patients in the study were from the U.S.
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    These and other weird aberrations about this study are mentioned in a link
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    that is in my report on the LOTTI study on my blog,
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    which I hope
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    you'll go and actually look at the study itself, and I write a little bit more
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    about LOTTI
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    and raise questions about why isn't this
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    information being
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    more widely publicized.
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    You won't find
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    any promotion of of the
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    information from LOTTIon the pharmaceutical funded
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    AIDS sites like AIDS.com...
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    AIDSmeds.com, poz.com.
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    thebody.com...
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    which is which is just
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    inexcusable to me.
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    I know of friends and other people who are on HAART,
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    and i support their choices in the decision to take
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    those drugs.
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    My point is that
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    decisions...
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    we need information
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    to make informed decisions.
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    This is important information that every person
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    who is facing
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    this choice should have.
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    I know people who are
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    having problems with the drugs but are
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    scared to death, basically, to quit
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    and
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    we need more
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    of this type of encouragement
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    that there's really not...
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    there's not as much to lose
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    to give it a try now and it doesn't work, you can go back on the drugs.
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    If it does,
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    you might never have to
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    go back on them.
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    That's my hope, at any rate
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    Go check out the blog. Its
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    resistanceisfruitful.com (new URL)
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    There's a link to in on the youtube page here.
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    Read the study, read my report, feel free to comment.
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    Thanks.
Title:
It's OK to stop taking AIDS meds: LOTTI Study
Description:

The LOTTI study found that patients who interrupted their highly active retroviral therapy (HAART) drugs for AIDS fared as well as those who took the toxic drugs continuously. In fact, more than one-fourth of those who quit their drugs never needed to start taking them again!
Structured Intermittent Therapy (STI) lowered the effects of toxicity, reduced treatment cost, and did not result in drug resistance.
Pharma funded AIDS sites, such as thebody.com, poz.com and aidsmed.com, are not actively informing their readers of the exciting results from this randomized, controlled, prospective study, which was published in the journal AIDS. Information is an essential component for making informed decisions.
Read more at my blog: http://resistanceisfruitful.com

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Duration:
07:41
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