1 00:00:06,634 --> 00:00:10,923 In 1977, the physicist Edward Purcell 2 00:00:10,947 --> 00:00:14,174 calculated that if you push a bacteria and then let go, 3 00:00:14,198 --> 00:00:16,923 it will stop in about a millionth of a second. 4 00:00:16,947 --> 00:00:21,149 In that time, it will have traveled less than the width of a single atom. 5 00:00:21,173 --> 00:00:24,640 The same holds true for a sperm and many other microbes. 6 00:00:24,664 --> 00:00:27,591 It all has to do with being really small. 7 00:00:27,615 --> 00:00:31,316 Microscopic creatures inhabit a world alien to us, 8 00:00:31,340 --> 00:00:34,699 where making it through an inch of water is an incredible endeavor. 9 00:00:34,723 --> 00:00:37,717 But why does size matter so much for a swimmer? 10 00:00:37,741 --> 00:00:40,741 What makes the world of a sperm so fundamentally different 11 00:00:40,765 --> 00:00:42,597 from that of a sperm whale? 12 00:00:42,621 --> 00:00:46,079 To find out, we need to dive into the physics of fluids. 13 00:00:46,103 --> 00:00:47,931 Here's a way to think about it. 14 00:00:47,955 --> 00:00:49,831 Imagine you are swimming in a pool. 15 00:00:49,855 --> 00:00:52,594 It's you and a whole bunch of water molecules. 16 00:00:52,618 --> 00:00:57,128 Water molecules outnumber you a thousand trillion trillion to one. 17 00:00:57,152 --> 00:01:00,502 So, pushing past them with your gigantic body is easy, 18 00:01:00,526 --> 00:01:02,688 but if you were really small, 19 00:01:02,712 --> 00:01:05,068 say you were about the size of a water molecule, 20 00:01:05,092 --> 00:01:07,107 all of a sudden, it's like you're swimming 21 00:01:07,131 --> 00:01:08,235 in a pool of people. 22 00:01:08,259 --> 00:01:11,575 Rather than simply swishing by all the teeny, tiny molecules, 23 00:01:11,599 --> 00:01:13,533 now every single water molecule 24 00:01:13,557 --> 00:01:16,045 is like another person you have to push past 25 00:01:16,069 --> 00:01:17,354 to get anywhere. 26 00:01:18,068 --> 00:01:20,955 In 1883, the physicist Osborne Reynolds 27 00:01:20,979 --> 00:01:23,078 figured out that there is one simple number 28 00:01:23,102 --> 00:01:25,992 that can predict how a fluid will behave. 29 00:01:26,016 --> 00:01:27,540 It's called the Reynolds number, 30 00:01:27,564 --> 00:01:31,581 and it depends on simple properties like the size of the swimmer, 31 00:01:31,605 --> 00:01:33,720 its speed, the density of the fluid, 32 00:01:33,744 --> 00:01:36,494 and the stickiness, or the viscosity, of the fluid. 33 00:01:37,566 --> 00:01:40,718 What this means is that creatures of very different sizes 34 00:01:40,742 --> 00:01:42,715 inhabit vastly different worlds. 35 00:01:42,739 --> 00:01:44,684 For example, because of its huge size, 36 00:01:44,708 --> 00:01:48,001 a sperm whale inhabits the large Reynolds number world. 37 00:01:48,723 --> 00:01:50,105 If it flaps its tail once, 38 00:01:50,129 --> 00:01:52,486 it can coast ahead for an incredible distance. 39 00:01:52,510 --> 00:01:56,184 Meanwhile, sperm live in a low Reynolds number world. 40 00:01:56,208 --> 00:01:58,357 If a sperm were to stop flapping its tail, 41 00:01:58,381 --> 00:02:00,912 it wouldn't even coast past a single atom. 42 00:02:01,266 --> 00:02:03,607 To imagine what it would feel like to be a sperm, 43 00:02:03,631 --> 00:02:06,270 you need to bring yourself down to its Reynolds number. 44 00:02:06,294 --> 00:02:09,154 Picture yourself in a tub of molasses with your arms moving 45 00:02:09,178 --> 00:02:12,118 about as slow as the minute hand of a clock, 46 00:02:12,142 --> 00:02:15,590 and you'd have a pretty good idea of what a sperm is up against. 47 00:02:15,614 --> 00:02:17,825 So, how do microbes manage to get anywhere? 48 00:02:17,849 --> 00:02:20,162 Well, many don't bother swimming at all. 49 00:02:20,186 --> 00:02:22,772 They just let the food drift to them. 50 00:02:22,796 --> 00:02:24,320 This is somewhat like a lazy cow 51 00:02:24,344 --> 00:02:27,049 that waits for the grass under its mouth to grow back. 52 00:02:27,073 --> 00:02:29,017 But many microbes do swim, 53 00:02:29,041 --> 00:02:31,985 and this is where those incredible adaptations come in. 54 00:02:32,009 --> 00:02:35,803 One trick they can use is to deform the shape of their paddle. 55 00:02:35,827 --> 00:02:37,526 By cleverly flexing their paddle 56 00:02:37,550 --> 00:02:41,401 to create more drag on the power stroke than on the recovery stroke, 57 00:02:41,425 --> 00:02:44,916 single-celled organisms like paramecia 58 00:02:44,940 --> 00:02:47,845 manage to inch their way through the crowd of water molecules. 59 00:02:47,869 --> 00:02:49,907 But there's an even more ingenious solution 60 00:02:49,931 --> 00:02:52,278 arrived at by bacteria and sperm. 61 00:02:52,786 --> 00:02:55,215 Instead of wagging their paddles back and forth, 62 00:02:55,239 --> 00:02:57,335 they wind them like a cork screw. 63 00:02:57,359 --> 00:02:59,182 Just as a cork screw on a wine bottle 64 00:02:59,206 --> 00:03:01,968 converts winding motion into forward motion, 65 00:03:01,992 --> 00:03:04,805 these tiny creatures spin their helical tails 66 00:03:04,829 --> 00:03:06,603 to push themselves forward 67 00:03:06,627 --> 00:03:10,360 in a world where water feels as thick as cork. 68 00:03:10,384 --> 00:03:12,485 Other strategies are even stranger. 69 00:03:12,509 --> 00:03:14,507 Some bacteria take Batman's approach. 70 00:03:14,531 --> 00:03:17,227 They use grappling hooks to pull themselves along. 71 00:03:17,251 --> 00:03:19,013 They can even use this grappling hook 72 00:03:19,037 --> 00:03:21,743 like a sling shot and fling themselves forward. 73 00:03:21,767 --> 00:03:24,195 Others use chemical engineering. 74 00:03:24,219 --> 00:03:27,485 H. pylori lives only in the slimy, acidic mucus 75 00:03:27,509 --> 00:03:29,234 inside our stomachs. 76 00:03:29,258 --> 00:03:32,697 It releases a chemical that thins out the surrounding mucus, 77 00:03:32,721 --> 00:03:34,650 allowing it to glide through slime. 78 00:03:34,674 --> 00:03:35,722 Maybe it's no surprise 79 00:03:35,746 --> 00:03:38,883 that these guys are also responsible for stomach ulcers. 80 00:03:39,383 --> 00:03:43,090 So, when you look really closely at our bodies and the world around us, 81 00:03:43,114 --> 00:03:45,088 you can see all sorts of tiny creatures 82 00:03:45,112 --> 00:03:48,957 finding clever ways to get around in a sticky situation. 83 00:03:48,981 --> 00:03:52,602 Without these adaptations, bacteria would never find their hosts, 84 00:03:52,626 --> 00:03:55,581 and sperms would never make it to their eggs, 85 00:03:55,605 --> 00:03:57,938 which means you would never get stomach ulcers, 86 00:03:57,962 --> 00:04:00,462 but you would also never be born in the first place. 87 00:04:00,486 --> 00:04:01,486 (Pop)