0:00:00.949,0:00:02.773 I'm thrilled to be here tonight 0:00:02.773,0:00:05.152 to share with you something[br]we've been working on 0:00:05.152,0:00:07.242 for over two years, 0:00:07.242,0:00:09.796 and it's in the area[br]of additive manufacturing, 0:00:09.796,0:00:12.513 also known as 3D printing. 0:00:12.513,0:00:14.231 You see this object here. 0:00:14.231,0:00:18.039 It looks fairly simple,[br]but it's quite complex at the same time. 0:00:18.549,0:00:21.800 It's a set of concentric[br]geodesic structures 0:00:21.800,0:00:24.795 with linkages between each one. 0:00:24.795,0:00:30.797 In its context, it is not manufacturable[br]by traditional manufacturing techniques. 0:00:31.343,0:00:35.290 It has a symmetry such[br]that you can't injection mold it. 0:00:35.290,0:00:38.879 You can't even manufacture it[br]through milling. 0:00:39.470,0:00:42.117 This is a job for a 3D printer, 0:00:42.117,0:00:46.598 but most 3D printers would take between[br]three and 10 hours to fabricate it, 0:00:46.598,0:00:50.824 and we're going to take the risk tonight[br]to try to fabricate it onstage 0:00:50.824,0:00:53.401 during this 10-minute talk. 0:00:53.401,0:00:55.440 Wish us luck. 0:00:56.350,0:00:59.624 Now, 3D printing is actually a misnomer. 0:00:59.624,0:01:03.399 It's actually 2D printing[br]over and over again, 0:01:03.919,0:01:07.761 and it in fact uses the technologies[br]associated with 2D printing. 0:01:08.401,0:01:13.360 Think about inkjet printing where you[br]lay down ink on a page to make letters, 0:01:13.360,0:01:18.346 and then do that over and over again[br]to build up a three-dimensional object. 0:01:18.346,0:01:20.417 In microelectronics, they use something 0:01:20.417,0:01:22.737 called lithography to do[br]the same sort of thing, 0:01:22.737,0:01:24.945 to make the transistors[br]and integrated circuits 0:01:24.945,0:01:26.997 and build up a structure several times. 0:01:26.997,0:01:29.399 These are all 2D printing technologies. 0:01:30.099,0:01:33.987 Now, I'm a chemist,[br]a material scientist too, 0:01:33.987,0:01:36.711 and my co-inventors[br]are also material scientists, 0:01:36.711,0:01:39.010 one a chemist, one a physicist, 0:01:39.010,0:01:41.936 and we began to be[br]interested in 3D printing. 0:01:41.936,0:01:47.531 And very often, as you know,[br]new ideas are often simple connections 0:01:47.531,0:01:51.274 between people with different experiences[br]in different communities, 0:01:51.274,0:01:52.751 and that's our story. 0:01:53.591,0:01:56.122 Now, we were inspired 0:01:56.122,0:02:00.893 by the "Terminator 2" scene for T-1000, 0:02:00.893,0:02:05.836 and we thought, why couldn't a 3D printer[br]operate in this fashion, 0:02:06.426,0:02:10.362 where you have an object[br]arise out of a puddle 0:02:11.052,0:02:13.520 in essentially real time 0:02:13.520,0:02:15.749 with essentially no waste 0:02:15.749,0:02:18.071 to make a great object? 0:02:18.071,0:02:19.488 Okay, just like the movies. 0:02:19.488,0:02:22.877 And could we be inspired by Hollywood 0:02:22.877,0:02:26.384 and come up with ways[br]to actually try to get this to work? 0:02:26.384,0:02:28.450 And that was our challenge. 0:02:28.450,0:02:31.817 And our approach would be,[br]if we could do this, 0:02:31.817,0:02:35.671 then we could fundamentally address[br]the three issues holding back 3D printing 0:02:35.671,0:02:38.086 from being a manufacturing process. 0:02:38.086,0:02:40.617 One, 3D printing takes forever. 0:02:40.617,0:02:45.841 There are mushrooms that grow faster[br]than 3D printed parts. (Laughter) 0:02:47.281,0:02:49.417 The layer by layer process 0:02:49.417,0:02:52.319 leads to defects[br]in mechanical properties, 0:02:52.319,0:02:56.266 and if we could grow continuously,[br]we could eliminate those defects. 0:02:56.266,0:03:01.398 And in fact, if we could grow really fast,[br]we could also start using materials 0:03:01.398,0:03:06.042 that are self-curing,[br]and we could have amazing properties. 0:03:06.042,0:03:10.151 So if we could pull this off,[br]imitate Hollywood, 0:03:10.151,0:03:12.912 we could in fact address 3D manufacturing. 0:03:14.702,0:03:17.953 Our approach is to use[br]some standard knowledge 0:03:17.953,0:03:20.553 in polymer chemistry 0:03:20.553,0:03:27.152 to harness light and oxygen[br]to grow parts continuously. 0:03:27.152,0:03:30.099 Light and oxygen work in different ways. 0:03:30.099,0:03:33.141 Light can take a resin[br]and convert it to a solid, 0:03:33.141,0:03:35.295 can convert a liquid to a solid. 0:03:35.295,0:03:38.829 Oxygen inhibits that process. 0:03:38.829,0:03:42.080 So light and oxygen[br]are polar opposites from one another 0:03:42.080,0:03:44.588 from a chemical point of view, 0:03:44.588,0:03:48.001 and if we can control spatially[br]the light and oxygen, 0:03:48.001,0:03:49.948 we could control this process. 0:03:50.288,0:03:53.739 And we refer to this as CLIP.[br][Continuous Liquid Interface Production.] 0:03:53.739,0:03:55.615 It has three functional components. 0:03:56.465,0:04:00.326 One, it has a reservoir[br]that holds the puddle, 0:04:00.326,0:04:02.205 just like the T-1000. 0:04:02.205,0:04:04.621 At the bottom of the reservoir[br]is a special window. 0:04:04.621,0:04:06.112 I'll come back to that. 0:04:06.112,0:04:09.892 In addition, it has a stage[br]that will lower into the puddle 0:04:09.892,0:04:12.481 and pull the object out of the liquid. 0:04:12.481,0:04:16.285 The third component[br]is a digital light projection system 0:04:16.285,0:04:18.305 underneath the reservoir, 0:04:18.305,0:04:21.578 illuminating with light[br]in the ultraviolet region. 0:04:22.048,0:04:25.271 Now, the key is that this window[br]in the bottom of this reservoir, 0:04:25.271,0:04:28.150 it's a composite,[br]it's a very special window. 0:04:28.150,0:04:31.796 It's not only transparent to light[br]but it's permeable to oxygen. 0:04:31.796,0:04:34.455 It's got characteristics[br]like a contact lens. 0:04:35.435,0:04:37.716 So we can see how the process works. 0:04:37.716,0:04:41.130 You can start to see that[br]as you lower a stage in there, 0:04:41.130,0:04:45.309 in a traditional process,[br]with an oxygen-impermeable window, 0:04:45.309,0:04:47.148 you make a two-dimensional pattern 0:04:48.008,0:04:51.370 and you end up gluing that onto the window[br]with a traditional window, 0:04:51.370,0:04:54.922 and so in order to introduce[br]the next layer, you have to separate it, 0:04:54.922,0:04:58.451 introduce new resin, reposition it, 0:04:58.451,0:05:00.910 and do this process over and over again. 0:05:01.400,0:05:03.234 But with our very special window, 0:05:03.234,0:05:06.563 what we're able to do is,[br]with oxygen coming through the bottom 0:05:06.563,0:05:07.816 as light hits it, 0:05:09.256,0:05:11.926 that oxygen inhibits the reaction, 0:05:11.926,0:05:14.550 and we form a dead zone. 0:05:14.550,0:05:18.869 This dead zone is on the order[br]of tens of microns thick, 0:05:18.869,0:05:22.096 so that's two or three diameters[br]of a red blood cell, 0:05:22.096,0:05:24.627 right at the window interface[br]that remains a liquid, 0:05:24.627,0:05:26.577 and we pull this object up, 0:05:26.577,0:05:28.969 and as we talked about in a Science paper, 0:05:28.969,0:05:33.682 as we change the oxygen content,[br]we can change the dead zone thickness. 0:05:33.682,0:05:37.374 And so we have a number of key variables[br]that we control: oxygen content, 0:05:37.374,0:05:40.439 the light, the light intensity,[br]the dose to cure, 0:05:40.439,0:05:42.401 the viscosity, the geometry, 0:05:42.401,0:05:45.817 and we use very sophisticated software[br]to control this process. 0:05:46.697,0:05:49.460 The result is pretty staggering. 0:05:49.460,0:05:53.196 It's 25 to 100 times faster[br]than traditional 3D printers, 0:05:54.336,0:05:56.170 which is game-changing. 0:05:56.170,0:06:00.506 In addition, as our ability[br]to deliver liquid to that interface, 0:06:00.506,0:06:04.246 we can go 1,000 times faster I believe, 0:06:04.246,0:06:07.803 and that in fact opens up the opportunity[br]for generating a lot of heat, 0:06:07.803,0:06:11.866 and as a chemical engineer,[br]I get very excited at heat transfer 0:06:11.866,0:06:16.045 and the idea that we might one day[br]have water-cooled 3D printers, 0:06:16.045,0:06:18.437 because they're going so fast. 0:06:18.437,0:06:22.500 In addition, because we're growing things,[br]we eliminate the layers, 0:06:22.500,0:06:24.474 and the parts are monolithic. 0:06:24.474,0:06:26.564 You don't see the surface structure. 0:06:26.564,0:06:29.057 You have molecularly smooth surfaces. 0:06:29.057,0:06:33.297 And the mechanical properties[br]of most parts made in a 3D printer 0:06:33.297,0:06:37.593 are notorious for having properties[br]that depend on the orientation 0:06:37.593,0:06:41.354 with which how you printed it,[br]because of the layer-like structure. 0:06:41.354,0:06:43.699 But when you grow objects like this, 0:06:43.699,0:06:47.368 the properties are invariant[br]with the print direction. 0:06:47.368,0:06:50.317 These look like injection-molded parts, 0:06:50.317,0:06:53.729 which is very different[br]than traditional 3D manufacturing. 0:06:53.729,0:06:57.259 In addition, we're able to throw 0:06:57.259,0:07:00.835 the entire polymer[br]chemistry textbook at this, 0:07:00.835,0:07:04.826 and we're able to design chemistries[br]that can give rise to the properties 0:07:04.826,0:07:07.868 you really want in a 3D-printed object. 0:07:07.868,0:07:09.205 (Applause) 0:07:09.205,0:07:12.439 There it is. That's great. 0:07:14.049,0:07:17.627 You always take the risk that something[br]like this won't work onstage, right? 0:07:18.177,0:07:21.056 But we can have materials[br]with great mechanical properties. 0:07:21.056,0:07:23.494 For the first time, we can have elastomers 0:07:23.494,0:07:25.955 that are high elasticity[br]or high dampening. 0:07:25.955,0:07:29.368 Think about vibration control[br]or great sneakers, for example. 0:07:29.368,0:07:31.978 We can make materials[br]that have incredible strength, 0:07:32.828,0:07:36.404 high strength-to-weight ratio,[br]really strong materials, 0:07:36.404,0:07:38.517 really great elastomers, 0:07:38.517,0:07:41.242 so throw that in the audience there. 0:07:41.242,0:07:43.878 So great material properties. 0:07:43.878,0:07:47.293 And so the opportunity now,[br]if you actually make a part 0:07:47.293,0:07:50.973 that has the properties[br]to be a final part, 0:07:50.973,0:07:54.073 and you do it in game-changing speeds, 0:07:54.073,0:07:56.860 you can actually transform manufacturing. 0:07:56.860,0:07:59.716 Right now, in manufacturing,[br]what happens is, 0:07:59.716,0:08:02.678 the so-called digital thread[br]in digital manufacturing. 0:08:02.678,0:08:07.717 We go from a CAD drawing, a design,[br]to a prototype to manufacturing. 0:08:07.717,0:08:10.440 Often, the digital thread is broken[br]right at prototype, 0:08:10.440,0:08:12.872 because you can't go[br]all the way to manufacturing 0:08:12.872,0:08:16.587 because most parts don't have[br]the properties to be a final part. 0:08:16.587,0:08:18.978 We now can connect the digital thread 0:08:18.978,0:08:23.227 all the way from design[br]to prototyping to manufacturing, 0:08:23.227,0:08:26.176 and that opportunity[br]really opens up all sorts of things, 0:08:26.176,0:08:31.129 from better fuel-efficient cars[br]dealing with great lattice properties 0:08:31.129,0:08:33.080 with high strength-to-weight ratio, 0:08:33.080,0:08:36.508 new turbine blades,[br]all sorts of wonderful things. 0:08:37.468,0:08:42.623 Think about if you need a stent[br]in an emergency situation, 0:08:42.623,0:08:46.593 instead of the doctor pulling off[br]a stent out of the shelf 0:08:46.593,0:08:48.822 that was just standard sizes, 0:08:48.822,0:08:52.978 having a stent that's designed[br]for you, for your own anatomy 0:08:52.978,0:08:54.789 with your own tributaries, 0:08:54.789,0:08:58.038 printed in an emergency situation[br]in real time out of the properties 0:08:58.038,0:09:01.477 such that the stent could go away[br]after 18 months: really-game changing. 0:09:01.477,0:09:05.633 Or digital dentistry, and making[br]these kinds of structures 0:09:05.633,0:09:08.814 even while you're in the dentist chair. 0:09:08.814,0:09:11.530 And look at the structures[br]that my students are making 0:09:11.530,0:09:13.504 at the University of North Carolina. 0:09:13.504,0:09:16.313 These are amazing microscale structures. 0:09:16.313,0:09:19.309 You know, the world is really good[br]at nano-fabrication. 0:09:19.309,0:09:23.599 Moore's Law has driven things[br]from 10 microns and below. 0:09:23.599,0:09:25.201 We're really good at that, 0:09:25.201,0:09:29.241 but it's actually very hard to make things[br]from 10 microns to 1,000 microns, 0:09:29.241,0:09:31.261 the mesoscale. 0:09:31.261,0:09:34.094 And subtractive techniques[br]from the silicon industry 0:09:34.094,0:09:35.510 can't do that very well. 0:09:35.510,0:09:37.159 They can't etch wafers that well. 0:09:37.159,0:09:39.109 But this process is so gentle, 0:09:39.109,0:09:41.594 we can grow these objects[br]up from the bottom 0:09:41.594,0:09:43.590 using additive manufacturing 0:09:43.590,0:09:45.843 and make amazing things[br]in tens of seconds, 0:09:45.843,0:09:47.932 opening up new sensor technologies, 0:09:47.932,0:09:50.417 new drug delivery techniques, 0:09:50.417,0:09:54.149 new lab-on-a-chip applications,[br]really game-changing stuff. 0:09:55.149,0:09:59.983 So the opportunity of making[br]a part in real time 0:09:59.983,0:10:02.816 that has the properties to be a final part 0:10:02.816,0:10:05.792 really opens up 3D manufacturing, 0:10:05.792,0:10:08.992 and for us, this is very exciting,[br]because this really is owning 0:10:08.992,0:10:15.589 the intersection between hardware,[br]software and molecular science, 0:10:15.589,0:10:19.755 and I can't wait to see what designers[br]and engineers around the world 0:10:19.755,0:10:22.029 are going to be able to do[br]with this great tool. 0:10:22.499,0:10:24.618 Thanks for listening. 0:10:24.618,0:10:29.727 (Applause)