0:00:05.013,0:00:09.004 In this session, we shall talk about epidemics. 0:00:09.004,0:00:12.069 What do you understand by the term 'Epidemic'[br]or 'Outbreak'? 0:00:12.069,0:00:19.067 An epidemic (or outbreak) is the occurrence[br]of a disease in excess of what is expected 0:00:19.067,0:00:24.098 in a particular community, for a particular[br]group of people, within a certain period of 0:00:24.098,0:00:27.079 time. 0:00:27.079,0:00:35.026 Other terms related to epidemics: endemic[br]refers to the constant presence of a disease 0:00:35.026,0:00:40.037 or infectious agent within a given geographic[br]area or population group. 0:00:40.037,0:00:46.094 It is the usual or expected frequency of disease[br]within a population. 0:00:46.094,0:00:54.011 Pandemic, on the other hand refers to an epidemic[br]occurring simultaneously in multiple locations 0:00:54.011,0:00:59.023 world-wide. 0:00:59.023,0:01:04.096 As an example from your country, we see that[br]epidemics are the commonest Public Health 0:01:04.096,0:01:08.065 emergency in our districts across the East[br]Africa region. 0:01:08.065,0:01:15.077 In Uganda for example, 6 outbreaks occurred[br]in 8 months in 2007. 0:01:15.077,0:01:23.009 This included Cholera, Meningitis, Hepatitis[br]E, Marburg, Plague and Ebola. 0:01:23.009,0:01:31.929 Can you name 5 outbreaks that have occurred[br]recently in your district? 0:01:31.929,0:01:39.119 Common epidemic prone diseases include diarrhoeal[br]diseases including watery diarrhoea, Cholera, 0:01:39.119,0:01:41.719 dysentery and typhoid. 0:01:41.719,0:01:46.999 These are likely to occur in many districts[br]in the East Africa region. 0:01:46.999,0:01:51.609 Outbreaks of immunisable diseases like measles. 0:01:51.609,0:01:56.017 These are common because immunisation coverage[br]is low. 0:01:56.017,0:02:03.017 Malaria is endemic in most parts of Eastern[br]Africa, especially in low land areas; however, 0:02:03.017,0:02:08.075 outbreaks can occur in both low and highland[br]areas. 0:02:08.075,0:02:14.096 In areas where Malaria is endemic, outbreaks[br]occur when the threshold far exceeds what 0:02:14.096,0:02:20.064 is expected for that season. 0:02:20.064,0:02:26.003 Other epidemic prone diseases include Sexually[br]Transmitted Infections including HIV/AIDS, 0:02:26.003,0:02:36.047 Syphilis, Gonorrhea, and others, Plague, Hepatitis[br]E, a massive chemical poisoning, especially 0:02:36.047,0:02:43.047 from illicit alcohol, which has become a common[br]public health problem in Eastern 0:02:43.047,0:02:45.036 Africa. 0:02:45.036,0:02:50.006 Let us look at a case study 1. 0:02:50.006,0:02:57.053 Refer to the word document on your CD. 0:02:57.053,0:03:03.028 The questions: Is this a scenario that could[br]occur in your district? And how did the district 0:03:03.028,0:03:08.000 authorities establish that there is an outbreak? 0:03:08.000,0:03:14.067 In detecting an outbreak, we have to obtain[br]initial notification of the outbreak. 0:03:14.067,0:03:20.029 We receive information about the likelihood[br]of an outbreak from the community, and from 0:03:20.029,0:03:23.099 cases coming to health units, and from local[br]leaders. 0:03:23.099,0:03:32.051 We therefore have to have an effective early[br]warning system that is linked to the communities. 0:03:32.051,0:03:40.004 The golden rule in detecting outbreaks is[br]that every rumour must be investigated. 0:03:40.004,0:03:46.007 In detecting an outbreak, we must have a case[br]definition for the diseases and this should 0:03:46.007,0:03:52.035 be known by the frontline health workers and[br]then they must also be made for a community 0:03:52.035,0:03:53.084 case definition. 0:03:53.084,0:04:01.078 Secondly, there must be an un-expected rise[br]in new cases of these diseases beyond the 0:04:01.078,0:04:05.096 threshold. 0:04:05.096,0:04:13.009 You look at the word document station activities[br]and read the standard case definitions for 0:04:13.009,0:04:16.039 some academic prone diseases. 0:04:16.039,0:04:26.079 For instance, what is the standard case definition[br]for polio, measles, cholera, bola, and bacterial 0:04:26.079,0:04:28.075 meningitis? 0:04:28.075,0:04:34.019 Case definitions may be changed according[br]to the locality and the nature of the symptoms 0:04:34.019,0:04:39.097 presenting in a particular outbreak situation. 0:04:39.097,0:04:46.097 The District Rapid Reaction Team (RRT) can develop a working case[br]definition where there is no standard case 0:04:46.097,0:04:53.072 definition depending on common symptoms and[br]risk factors related to the syndrome that 0:04:53.072,0:04:56.002 has broken out. 0:04:56.002,0:05:00.001 Can you suggest a case definition for the[br]following? 0:05:00.001,0:05:05.046 1. An outbreak of sudden alcohol related illness[br]and deaths in zone X 0:05:05.046,0:05:16.063 2. An outbreak of dysentery in camp Y[br]3. An outbreak of sudden food-related illness 0:05:16.063,0:05:21.013 and deaths in a village Z 0:05:21.013,0:05:27.002 Some epidemic prone diseases exist in the[br]community even without an outbreak. 0:05:27.002,0:05:33.007 An example is malaria, which is prevalent[br]in many parts of Eastern Africa. 0:05:33.007,0:05:39.081 For an outbreak to be declared, there must[br]be a sharp rise in cases beyond the expected 0:05:39.081,0:05:44.006 threshold for a particular season. 0:05:44.006,0:05:50.002 Some epidemic prone diseases do not exist[br]normally in the community. 0:05:50.002,0:05:54.048 The occurrence of just one confirmed case[br]is considered an outbreak. 0:05:54.048,0:05:58.038 An example is cholera. 0:05:58.038,0:06:01.009 Some epidemic prone diseases are rare and[br]highly deadly when they occur. 0:06:01.009,0:06:06.083 We do not have to wait for confirmation of[br]a case. 0:06:06.083,0:06:10.059 Just one suspected case is enough to consider[br]an outbreak. 0:06:10.059,0:06:13.081 An example is ebola. 0:06:13.081,0:06:18.061 Therefore, thresholds differ from disease[br]to disease. 0:06:18.061,0:06:21.062 In cholera, just one confirmed case. 0:06:21.062,0:06:24.019 In ebola, one suspected case. 0:06:24.019,0:06:31.009 In measles, a cluster of 5 or more suspected[br]cases OR at least 3 confirmed positive cases 0:06:31.009,0:06:37.021 in a catchment area of a health facility occurring[br]in one month. 0:06:37.021,0:06:44.021 For malaria, because it is embedded in many[br]parts of Eastern Africa, an outbreak occurs 0:06:44.021,0:06:53.038 when there is a sharp seasonal rise in cases[br]beyond the usual number of expected cases. 0:06:53.038,0:07:04.056 Let us look at the second case study, which[br]is one of the documents on the CD. 0:07:04.056,0:07:11.056 Let us read through this case study, and the[br]questions for general discussion are: How 0:07:11.056,0:07:17.026 do you think the District and Ministry of[br]Health officials went about investigating 0:07:17.026,0:07:19.079 this particular outbreak? 0:07:19.079,0:07:25.005 What do you understand by the term 'early[br]response'? 0:07:25.005,0:07:37.699 Steps in investigating an outbreak: Step 1.[br]Initial response and confirmation of outbreak. 0:07:37.699,0:07:45.037 It is important to assemble a team and prepare[br]for an initial field visit as soon as possible. 0:07:45.037,0:07:51.075 Two, it is important to choose a working case[br]definition and confirm cases. 0:07:51.075,0:07:54.083 Three, find cases systematically. 0:07:54.083,0:08:01.003 Four, confirm whether there is an outbreak[br]by comparing occurrence of cases with thresholds. 0:08:01.003,0:08:07.084 And five, describe who is affected, when and[br]where? 0:08:07.084,0:08:14.084 Step 2: Manage and identify cases. 0:08:14.084,0:08:22.016 Establish a district task force and allocate[br]them their responsibilities. 0:08:22.016,0:08:30.015 Use the working case definition to find cases[br]and set up a treatment centre. 0:08:30.015,0:08:34.579 Step 3: Set up immediate control measures. 0:08:34.579,0:08:38.081 Treat cases to interrupt transmission and[br]reduce deaths. 0:08:38.081,0:08:45.022 Consider vaccination, disinfection and protective[br]wear. 0:08:45.022,0:08:48.056 Provide health education to those at risk. 0:08:48.056,0:08:53.077 Communicate clearly to reduce panic and prevent[br]spread of the disease. 0:08:53.077,0:08:57.061 Step 4: Address the resource gaps. 0:08:57.061,0:09:02.014 Ensure adequate medical supplies and logistics[br]to handle cases. 0:09:02.014,0:09:07.062 Look for additional resources to address the[br]gaps and contact Ministry of Health and partner 0:09:07.062,0:09:12.017 agencies in case the resources are inadequate. 0:09:12.017,0:09:19.085 Step 5: Determine responsible factors for the [br]outbreak and make a report. 0:09:19.085,0:09:24.013 Analyse available information to establish[br]the risk factors. 0:09:24.013,0:09:29.062 Prepare a report and ensure that it is disseminated[br]to those who need to know and those who need 0:09:29.062,0:09:30.069 to take action. 0:09:30.069,0:09:48.029 On the report, you ought to recommend and[br]implement priority control measures. 0:09:48.029,0:09:42.008 And Step 6: Be on your guard. 0:09:42.008,0:09:49.019 Strengthen the existing surveillance system[br]to find cases actively and learn from this 0:09:49.019,0:09:52.069 outbreak to respond better in future. 0:09:52.069,0:09:58.076 Put in place measures to prevent similar outbreaks[br]in the future. 0:09:58.076,9:59:59.000 Thank you for listening.