1 00:00:06,825 --> 00:00:09,077 Picture warm, gooey cookies, 2 00:00:09,101 --> 00:00:12,052 crunchy candies, velvety cakes, 3 00:00:12,076 --> 00:00:14,670 waffle cones piled high with ice cream. 4 00:00:14,693 --> 00:00:16,646 Is your mouth watering? 5 00:00:16,670 --> 00:00:17,867 Are you craving dessert? 6 00:00:17,891 --> 00:00:18,922 Why? 7 00:00:18,946 --> 00:00:23,676 What happens in the brain that makes sugary foods so hard to resist? 8 00:00:23,700 --> 00:00:27,089 Sugar is a general term used to describe a class of molecules 9 00:00:27,113 --> 00:00:28,403 called carbohydrates, 10 00:00:28,427 --> 00:00:31,254 and it's found in a wide variety of food and drink. 11 00:00:31,278 --> 00:00:34,418 Just check the labels on sweet products you buy. 12 00:00:34,442 --> 00:00:36,910 Glucose, fructose, sucrose, 13 00:00:36,934 --> 00:00:39,783 maltose, lactose, dextrose, and starch 14 00:00:39,807 --> 00:00:41,762 are all forms of sugar. 15 00:00:41,786 --> 00:00:43,717 So are high-fructose corn syrup, 16 00:00:43,741 --> 00:00:46,270 fruit juice, raw sugar, and honey. 17 00:00:46,709 --> 00:00:49,638 And sugar isn't just in candies and desserts, 18 00:00:49,662 --> 00:00:51,186 it's also added to tomato sauce, 19 00:00:51,188 --> 00:00:55,676 yogurt, dried fruit, flavored waters, or granola bars. 20 00:00:55,700 --> 00:00:58,663 Since sugar is everywhere, it's important to understand 21 00:00:58,687 --> 00:00:59,882 how it affects the brain. 22 00:00:59,906 --> 00:01:02,251 What happens when sugar hits your tongue? 23 00:01:02,275 --> 00:01:05,206 And does eating a little bit of sugar make you crave more? 24 00:01:05,753 --> 00:01:07,323 You take a bite of cereal. 25 00:01:07,347 --> 00:01:10,504 The sugars it contains activate the sweet-taste receptors, 26 00:01:10,528 --> 00:01:12,746 part of the taste buds on the tongue. 27 00:01:12,770 --> 00:01:15,747 These receptors send a signal up to the brain stem, 28 00:01:15,771 --> 00:01:19,237 and from there, it forks off into many areas of the forebrain, 29 00:01:19,261 --> 00:01:21,789 one of which is the cerebral cortex. 30 00:01:21,813 --> 00:01:25,983 Different sections of the cerebral cortex process different tastes: 31 00:01:26,007 --> 00:01:27,971 bitter, salty, umami, 32 00:01:27,995 --> 00:01:29,799 and, in our case, sweet. 33 00:01:29,823 --> 00:01:33,416 From here, the signal activates the brain's reward system. 34 00:01:33,440 --> 00:01:37,101 This reward system is a series of electrical and chemical pathways 35 00:01:37,125 --> 00:01:39,725 across several different regions of the brain. 36 00:01:39,749 --> 00:01:41,035 It's a complicated network, 37 00:01:41,059 --> 00:01:44,484 but it helps answer a single, subconscious question: 38 00:01:44,508 --> 00:01:45,853 should I do that again? 39 00:01:45,877 --> 00:01:49,477 That warm, fuzzy feeling you get when you taste Grandma's chocolate cake? 40 00:01:49,501 --> 00:01:51,380 That's your reward system saying, 41 00:01:51,404 --> 00:01:52,916 "Mmm, yes!" 42 00:01:52,940 --> 00:01:55,273 And it's not just activated by food. 43 00:01:55,297 --> 00:01:57,583 Socializing, sexual behavior, and drugs 44 00:01:57,607 --> 00:02:00,710 are just a few examples of things and experiences 45 00:02:00,734 --> 00:02:03,277 that also activate the reward system. 46 00:02:03,301 --> 00:02:08,645 But overactivating this reward system kickstarts a series of unfortunate events: 47 00:02:08,669 --> 00:02:12,300 loss of control, craving, and increased tolerance to sugar. 48 00:02:13,158 --> 00:02:15,231 Let's get back to our bite of cereal. 49 00:02:15,255 --> 00:02:18,888 It travels down into your stomach and eventually into your gut. 50 00:02:18,912 --> 00:02:19,925 And guess what? 51 00:02:19,949 --> 00:02:22,356 There are sugar receptors here, too. 52 00:02:22,380 --> 00:02:24,731 They are not taste buds, but they do send signals 53 00:02:24,755 --> 00:02:26,563 telling your brain that you're full 54 00:02:26,587 --> 00:02:28,730 or that your body should produce more insulin 55 00:02:28,754 --> 00:02:30,979 to deal with the extra sugar you're eating. 56 00:02:31,596 --> 00:02:34,539 The major currency of our reward system is dopamine, 57 00:02:34,563 --> 00:02:37,129 an important chemical or neurotransmitter. 58 00:02:37,153 --> 00:02:39,660 There are many dopamine receptors in the forebrain, 59 00:02:39,684 --> 00:02:41,816 but they're not evenly distributed. 60 00:02:41,840 --> 00:02:44,624 Certain areas contain dense clusters of receptors, 61 00:02:44,648 --> 00:02:48,311 and these dopamine hot spots are a part of our reward system. 62 00:02:48,898 --> 00:02:51,549 Drugs like alcohol, nicotine, or heroin 63 00:02:51,573 --> 00:02:53,342 send dopamine into overdrive, 64 00:02:53,366 --> 00:02:56,425 leading some people to constantly seek that high, 65 00:02:56,449 --> 00:02:58,170 in other words, to be addicted. 66 00:02:58,645 --> 00:03:03,532 Sugar also causes dopamine to be released, though not as violently as drugs. 67 00:03:03,556 --> 00:03:06,665 And sugar is rare among dopamine-inducing foods. 68 00:03:06,689 --> 00:03:08,628 Broccoli, for example, has no effect, 69 00:03:08,652 --> 00:03:10,088 which probably explains 70 00:03:10,112 --> 00:03:12,813 why it's so hard to get kids to eat their veggies. 71 00:03:13,295 --> 00:03:14,851 Speaking of healthy foods, 72 00:03:14,875 --> 00:03:17,690 let's say you're hungry and decide to eat a balanced meal. 73 00:03:17,714 --> 00:03:21,325 You do, and dopamine levels spike in the reward system hot spots. 74 00:03:21,349 --> 00:03:24,706 But if you eat that same dish many days in a row, 75 00:03:24,730 --> 00:03:28,974 dopamine levels will spike less and less, eventually leveling out. 76 00:03:28,998 --> 00:03:30,760 That's because when it comes to food, 77 00:03:30,784 --> 00:03:34,931 the brain evolved to pay special attention to new or different tastes. 78 00:03:34,955 --> 00:03:36,061 Why? 79 00:03:36,085 --> 00:03:37,245 Two reasons: 80 00:03:37,269 --> 00:03:39,785 first, to detect food that's gone bad. 81 00:03:39,809 --> 00:03:42,729 And second, because the more variety we have in our diet, 82 00:03:42,753 --> 00:03:45,852 the more likely we are to get all the nutrients we need. 83 00:03:45,876 --> 00:03:47,227 To keep that variety up, 84 00:03:47,251 --> 00:03:49,639 we need to be able to recognize a new food, 85 00:03:49,663 --> 00:03:53,520 and more importantly, we need to want to keep eating new foods. 86 00:03:53,544 --> 00:03:57,343 And that's why the dopamine levels off when a food becomes boring. 87 00:03:57,367 --> 00:03:58,942 Now, back to that meal. 88 00:03:58,966 --> 00:04:02,068 What happens if in place of the healthy, balanced dish, 89 00:04:02,092 --> 00:04:04,283 you eat sugar-rich food instead? 90 00:04:04,307 --> 00:04:07,315 If you rarely eat sugar or don't eat much at a time, 91 00:04:07,339 --> 00:04:09,949 the effect is similar to that of the balanced meal. 92 00:04:09,973 --> 00:04:13,702 But if you eat too much, the dopamine response does not level out. 93 00:04:13,726 --> 00:04:17,721 In other words, eating lots of sugar will continue to feel rewarding. 94 00:04:17,745 --> 00:04:21,129 In this way, sugar behaves a little bit like a drug. 95 00:04:21,153 --> 00:04:24,597 It's one reason people seem to be hooked on sugary foods. 96 00:04:24,621 --> 00:04:27,513 So, think back to all those different kinds of sugar. 97 00:04:27,537 --> 00:04:30,904 Each one is unique, but every time any sugar is consumed, 98 00:04:30,928 --> 00:04:35,265 it kickstarts a domino effect in the brain that sparks a rewarding feeling. 99 00:04:35,289 --> 00:04:38,696 Too much, too often, and things can go into overdrive. 100 00:04:38,720 --> 00:04:42,951 So, yes, overconsumption of sugar can have addictive effects on the brain, 101 00:04:42,975 --> 00:04:46,178 but a wedge of cake once in a while won't hurt you.