WEBVTT 00:00:00.763 --> 00:00:03.378 Organic chemists make molecules, 00:00:03.378 --> 00:00:05.194 very complicated molecules, 00:00:05.194 --> 00:00:08.878 by chopping up a big molecule into small molecules 00:00:08.878 --> 00:00:10.739 and reverse engineering. 00:00:10.739 --> 00:00:11.778 And as a chemist, 00:00:11.778 --> 00:00:15.245 one of the things I wanted to ask my research group a couple of years ago is, 00:00:15.245 --> 00:00:19.396 could we make a really cool universal chemistry set? 00:00:19.396 --> 00:00:24.429 In essence, could we "app" chemistry? NOTE Paragraph 00:00:24.429 --> 00:00:27.612 Now what would this mean, and how would we do it? 00:00:27.612 --> 00:00:29.583 Well to start to do this, 00:00:29.583 --> 00:00:31.315 we took a 3D printer 00:00:31.315 --> 00:00:35.617 and we started to print our beakers and our test tubes on one side 00:00:35.617 --> 00:00:39.682 and then print the molecule at the same time on the other side 00:00:39.682 --> 00:00:42.836 and combine them together in what we call reactionware. 00:00:42.836 --> 00:00:47.270 And so by printing the vessel and doing the chemistry at the same time, 00:00:47.270 --> 00:00:52.437 we may start to access this universal toolkit of chemistry. NOTE Paragraph 00:00:52.437 --> 00:00:53.985 Now what could this mean? 00:00:53.985 --> 00:00:59.253 Well if we can embed biological and chemical networks like a search engine, 00:00:59.253 --> 00:01:02.402 so if you have a cell that's ill that you need to cure 00:01:02.402 --> 00:01:04.121 or bacteria that you want to kill, 00:01:04.121 --> 00:01:06.452 if you have this embedded in your device 00:01:06.452 --> 00:01:08.901 at the same time, and you do the chemistry, 00:01:08.901 --> 00:01:12.502 you may be able to make drugs in a new way. NOTE Paragraph 00:01:12.502 --> 00:01:14.902 So how are we doing this in the lab? 00:01:14.902 --> 00:01:18.001 Well it requires software, it requires hardware 00:01:18.001 --> 00:01:20.367 and it requires chemical inks. 00:01:20.367 --> 00:01:21.820 And so the really cool bit is, 00:01:21.820 --> 00:01:24.867 the idea is that we want to have a universal set of inks 00:01:24.867 --> 00:01:27.136 that we put out with the printer, 00:01:27.136 --> 00:01:31.418 and you download the blueprint, the organic chemistry for that molecule 00:01:31.418 --> 00:01:34.418 and you make it in the device. 00:01:34.418 --> 00:01:39.985 And so you can make your molecule in the printer using this software. NOTE Paragraph 00:01:39.985 --> 00:01:42.184 So what could this mean? 00:01:42.184 --> 00:01:47.131 Well, ultimately, it could mean that you could print your own medicine. 00:01:47.131 --> 00:01:49.100 And this is what we're doing in the lab at the moment. NOTE Paragraph 00:01:49.100 --> 00:01:51.002 But to take baby steps to get there, 00:01:51.002 --> 00:01:53.835 first of all we want to look at drug design and production, 00:01:53.835 --> 00:01:56.485 or drug discovery and manufacturing. 00:01:56.485 --> 00:01:59.484 Because if we can manufacture it after we've discovered it, 00:01:59.484 --> 00:02:01.618 we could deploy it anywhere. 00:02:01.618 --> 00:02:03.734 You don't need to go to the chemist anymore. 00:02:03.734 --> 00:02:06.102 We can print drugs at point of need. 00:02:06.102 --> 00:02:08.757 We can download new diagnostics. 00:02:08.757 --> 00:02:10.768 Say a new super bug has emerged. 00:02:10.768 --> 00:02:12.385 You put it in your search engine, 00:02:12.385 --> 00:02:15.518 and you create the drug to treat the threat. 00:02:15.518 --> 00:02:19.206 So this allows you on-the-fly molecular assembly. NOTE Paragraph 00:02:19.206 --> 00:02:22.201 But perhaps for me the core bit going into the future 00:02:22.201 --> 00:02:25.551 is this idea of taking your own stem cells, 00:02:25.551 --> 00:02:27.318 with your genes and your environment, 00:02:27.318 --> 00:02:30.767 and you print your own personal medicine. NOTE Paragraph 00:02:30.767 --> 00:02:33.019 And if that doesn't seem fanciful enough, 00:02:33.019 --> 00:02:35.067 where do you think we're going to go? 00:02:35.067 --> 00:02:39.651 Well, you're going to have your own personal matter fabricator. 00:02:39.651 --> 00:02:41.551 Beam me up, Scotty. NOTE Paragraph 00:02:41.551 --> 00:02:44.900 (Applause)