WEBVTT 00:00:10.240 --> 00:00:12.766 Everyone has something that motivates them. 00:00:12.766 --> 00:00:14.515 For some people it's money. 00:00:14.515 --> 00:00:16.756 For some, it may be recognition, 00:00:16.756 --> 00:00:19.795 and others, maybe chocolate. 00:00:20.495 --> 00:00:22.265 If you're one of my research animals, 00:00:22.265 --> 00:00:24.225 it's the beloved Froot Loop. 00:00:24.225 --> 00:00:27.003 They absolutely love these as treats. 00:00:27.003 --> 00:00:29.017 They're easy for them to put in their mouth, 00:00:29.017 --> 00:00:30.497 and most importantly, 00:00:30.497 --> 00:00:32.528 they're packed with sugar. 00:00:33.248 --> 00:00:36.284 In our lab, we study the brain chemical dopamine. 00:00:36.754 --> 00:00:38.752 Dopamine is involved in movement, 00:00:38.752 --> 00:00:41.779 most notably implicated in Parkinson's disease, 00:00:41.779 --> 00:00:44.534 motivation and reward. 00:00:44.754 --> 00:00:45.793 We study dopamine 00:00:45.793 --> 00:00:48.775 in relation to learning and memory tasks. 00:00:48.775 --> 00:00:51.264 Our rats learn to run in a maze, 00:00:51.264 --> 00:00:53.754 and if they complete the task correctly, 00:00:53.754 --> 00:00:56.510 they receive a food reward at the end. 00:00:56.510 --> 00:01:00.527 We study and record when dopamine is released 00:01:00.527 --> 00:01:02.760 as the rats are completing this task. 00:01:02.760 --> 00:01:06.770 Look, he is even smiling! (Laughter) 00:01:06.770 --> 00:01:10.023 Dopamine helps activate the learning centers in the brain. 00:01:10.023 --> 00:01:11.791 So if dopamine is released 00:01:11.791 --> 00:01:13.229 as you're learning something, 00:01:13.229 --> 00:01:16.727 it will help you remember that information 00:01:16.727 --> 00:01:19.042 at a later date. 00:01:19.042 --> 00:01:20.276 For example, 00:01:20.276 --> 00:01:23.258 I had a chemistry professor on the very first day of class, 00:01:23.258 --> 00:01:27.240 do an intense reaction with lots of flames and smoke. 00:01:27.240 --> 00:01:28.764 He then explained 00:01:28.764 --> 00:01:32.273 how and why this chemical reaction took place. 00:01:32.273 --> 00:01:33.505 This reaction was done 00:01:33.505 --> 00:01:35.742 just using regular tap water and sodium. 00:01:36.512 --> 00:01:39.245 After he explained how this reaction worked, 00:01:39.245 --> 00:01:41.231 I'll never forget exactly 00:01:41.231 --> 00:01:45.280 how those electrons are moved in that reaction. 00:01:46.490 --> 00:01:49.260 It is likely that as this reaction was taking place, 00:01:49.260 --> 00:01:51.516 dopamine was being released in my brain. 00:01:51.516 --> 00:01:54.248 Of course, since I don't have any of our lab's electrodes 00:01:54.248 --> 00:01:57.253 placed in my brain, we won't know for sure. 00:01:57.253 --> 00:02:00.265 On the left is a picture of the electrodes 00:02:00.265 --> 00:02:01.767 we build in our lab. 00:02:01.767 --> 00:02:05.264 The electrode end consists of a single strand of carbon fiber. 00:02:05.264 --> 00:02:09.519 It's about one-tenth the diameter of the strand of human hair. 00:02:09.519 --> 00:02:11.253 We then implant these electrodes 00:02:11.253 --> 00:02:13.247 in freely moving animals, 00:02:13.247 --> 00:02:15.801 and record when dopamine is released, 00:02:15.801 --> 00:02:18.529 as they complete maze tasks. 00:02:20.739 --> 00:02:21.762 As you can see, 00:02:21.762 --> 00:02:23.500 the rat brain is very small. 00:02:23.500 --> 00:02:25.246 It's about the size of a nickel. 00:02:25.246 --> 00:02:27.653 And the area of the brain that we're trying to reach, 00:02:27.653 --> 00:02:29.783 is about the size of a pea. 00:02:29.783 --> 00:02:32.498 We implant these electrodes in an area of the brain, 00:02:32.498 --> 00:02:37.772 that's known to have a high number of dopamine neurons. 00:02:38.772 --> 00:02:41.268 One of my main hobbies is photography. 00:02:41.268 --> 00:02:43.044 So, for the background of my talk, 00:02:43.044 --> 00:02:45.762 I thought I would take you all on a tour of my lab, 00:02:45.762 --> 00:02:47.758 by way of my photography. 00:02:48.488 --> 00:02:50.264 These are just a few of the things 00:02:50.264 --> 00:02:51.523 we use in our lab 00:02:51.523 --> 00:02:54.230 to help us record dopamine. 00:02:55.760 --> 00:02:59.761 So what can we do to increase dopamine in our brain? 00:02:59.761 --> 00:03:02.745 Exercise, is a great way to increase dopamine. 00:03:02.745 --> 00:03:05.749 Exercise will increase dopamine release in your brain, 00:03:05.749 --> 00:03:07.746 as well as other neurochemicals, 00:03:07.746 --> 00:03:08.762 such as endorphins 00:03:08.762 --> 00:03:11.494 which are the brain's natural painkillers. 00:03:11.494 --> 00:03:12.771 Eating properly, 00:03:12.771 --> 00:03:15.006 is another great way to increase dopamine. 00:03:15.006 --> 00:03:17.510 Specifically, eating foods rich in tyrosine, 00:03:17.510 --> 00:03:19.765 which is a precursor to dopamine, 00:03:19.765 --> 00:03:22.748 will help, increase the available dopamine in the brain. 00:03:22.748 --> 00:03:24.235 Foods rich in tyrosine 00:03:24.235 --> 00:03:26.243 include things such as: Avocados, 00:03:26.243 --> 00:03:28.275 almonds and bananas. 00:03:29.495 --> 00:03:31.508 Another great way to release dopamine, 00:03:31.508 --> 00:03:33.501 is doing something rewarding to you. 00:03:33.501 --> 00:03:34.736 This can be something 00:03:34.736 --> 00:03:37.079 as easy as checking something off your to-do list, 00:03:37.079 --> 00:03:40.232 or perhaps volunteering at a community center. 00:03:40.232 --> 00:03:41.742 And of course, 00:03:41.742 --> 00:03:44.746 one of my personal favorite ways, to increase dopamine, 00:03:44.746 --> 00:03:47.172 is sex. (Laughter) 00:03:48.498 --> 00:03:52.026 Sex releases many beneficial chemicals in the brain 00:03:52.026 --> 00:03:53.501 in addition to dopamine, 00:03:53.501 --> 00:03:54.749 such as oxytocin, 00:03:54.749 --> 00:03:57.247 which is implicated in human bonding. 00:03:57.247 --> 00:03:58.248 Serotonin, 00:03:58.248 --> 00:04:01.248 which relates to happiness and a feeling of well-being. 00:04:01.738 --> 00:04:03.261 And norepinephrine, 00:04:03.261 --> 00:04:04.774 which increases alertness. 00:04:04.774 --> 00:04:07.532 So how can we use this information? 00:04:07.532 --> 00:04:09.768 Professors can develop new and exciting ways, 00:04:09.768 --> 00:04:12.267 to deliver information to students. 00:04:12.267 --> 00:04:14.247 It doesn't have to be as exciting 00:04:14.247 --> 00:04:15.770 as involving flames and explosions 00:04:15.770 --> 00:04:18.230 like my chemistry professor. 00:04:18.230 --> 00:04:19.750 It can be as simple as 00:04:19.750 --> 00:04:21.768 having students do a hands-on experience, 00:04:21.768 --> 00:04:25.256 or perhaps using the students as props 00:04:25.256 --> 00:04:27.501 to explain a difficult concept. 00:04:27.501 --> 00:04:30.745 Professors, get away from the traditional monologue lectures. 00:04:30.745 --> 00:04:32.773 It'll be more rewarding for you, 00:04:32.773 --> 00:04:36.241 and will stimulate the students to promote long-term learning. 00:04:36.241 --> 00:04:39.233 Let's get those dopamine neurons firing. 00:04:39.233 --> 00:04:41.520 Thank you. (Applause)