0:00:10.240,0:00:12.766 Everyone has something[br]that motivates them. 0:00:12.766,0:00:14.515 For some people [br]it's money. 0:00:14.515,0:00:16.756 For some,[br]it maybe recognition, 0:00:16.756,0:00:19.795 and others,[br]maybe chocolate. 0:00:20.495,0:00:22.265 If you're one [br]of my research animals, 0:00:22.265,0:00:24.225 it's the beloved Froot Loops. 0:00:24.225,0:00:27.003 They absolutely love [br]these as treats. 0:00:27.003,0:00:29.017 They're easy for them [br]to put in their mouth, 0:00:29.017,0:00:30.497 and most importantly, 0:00:30.497,0:00:32.528 they're packed with sugar. 0:00:33.248,0:00:36.284 In our lab, we study[br]the brain chemical dopamine. 0:00:36.754,0:00:38.752 Dopamine is involved in movement, 0:00:38.752,0:00:41.779 most notably implicated[br]in Parkinson's disease, 0:00:41.779,0:00:44.534 motivation and reward. 0:00:44.754,0:00:45.793 We study dopamine 0:00:45.793,0:00:48.775 in relation to learning[br]and memory tasks. 0:00:48.775,0:00:51.264 Our rats learn[br]to run in a maze, 0:00:51.264,0:00:53.754 and if they complete[br]the task correctly, 0:00:53.754,0:00:56.510 they receive [br]a food reward at the end. 0:00:56.510,0:01:00.527 We study and record[br]when dopamine is released 0:01:00.527,0:01:02.760 as the rats are completing[br]these tasks. 0:01:02.760,0:01:06.770 Look, he is even smiling![br](Laughter) 0:01:06.770,0:01:10.023 Dopamine helps activate[br]the learning centers in the brain. 0:01:10.023,0:01:11.791 So if dopamine is released 0:01:11.791,0:01:13.229 as you're learning something, 0:01:13.229,0:01:16.727 it will help you [br]remember that information 0:01:16.727,0:01:19.042 at a later date. 0:01:19.042,0:01:20.276 For example,[br] 0:01:20.276,0:01:23.258 I had a chemistry professor [br]on the very first day of class, 0:01:23.258,0:01:27.240 do an intense reaction[br]with lots of flames and smoke. 0:01:27.240,0:01:28.764 He then explained 0:01:28.764,0:01:32.273 how and why this chemical [br]reaction took place. 0:01:32.273,0:01:33.505 This reaction was done 0:01:33.505,0:01:35.742 just using regular [br]tap water and sodium. 0:01:36.512,0:01:39.245 After he explained [br]how this reaction worked, 0:01:39.245,0:01:41.231 I'll never forget exactly 0:01:41.231,0:01:45.280 how those electrons[br]are moved in that reaction. 0:01:46.490,0:01:49.260 Is likely as this reaction [br]was taking place, 0:01:49.260,0:01:51.516 dopamine was being released[br]in my brain. 0:01:51.516,0:01:54.248 Of course, since I don't have[br]any of our labs electrodes 0:01:54.248,0:01:57.253 placed in my brain,[br]we won't know for sure. 0:01:57.253,0:02:00.265 On the left[br]is a picture of the electrodes 0:02:00.265,0:02:01.767 we build in our lab. 0:02:01.767,0:02:05.264 The electrode ink consists [br]of a single strand of carbon fiber. 0:02:05.264,0:02:09.519 It's about one-tenth the diameter[br]of the strand of human hair. 0:02:09.519,0:02:11.253 We then implant these electrodes 0:02:11.253,0:02:13.247 in freely moving animals, 0:02:13.247,0:02:15.801 and record[br]when dopamine is released, 0:02:15.801,0:02:18.529 as they complete maze tasks. 0:02:20.739,0:02:21.762 As you can see, 0:02:21.762,0:02:23.500 the rat brain is very small. 0:02:23.500,0:02:25.246 It's about the size of a nickel. 0:02:25.246,0:02:27.653 And the area of the brain[br]that we're trying to reach, 0:02:27.653,0:02:29.783 is about the size of a pea. 0:02:29.783,0:02:32.498 We implant these electrodes[br]in an area of the brain,[br] 0:02:32.498,0:02:37.772 that's known to have[br]a high number of dopamine neurons. 0:02:38.772,0:02:41.268 One of my main hobbies [br]is photography. 0:02:41.268,0:02:43.044 So, [br]for the background of my talk, 0:02:43.044,0:02:45.762 I thought I would take you[br]all on a tour of my lab, 0:02:45.762,0:02:47.758 by way of my photography. 0:02:48.488,0:02:50.264 These are just[br]a few of the things 0:02:50.264,0:02:51.523 we use in our lab 0:02:51.523,0:02:54.230 to help us record dopamine. 0:02:55.760,0:02:59.761 So what can we do [br]to increase dopamine in our brain? 0:02:59.761,0:03:02.745 Exercise, is a great way[br]to increase dopamine. 0:03:02.745,0:03:05.749 Exercise will increase [br]dopamine release in your brain, 0:03:05.749,0:03:07.746 as well as other neural chemicals, 0:03:07.746,0:03:08.762 such as endorphin 0:03:08.762,0:03:11.494 which are the brain's [br]natural painkillers. 0:03:11.494,0:03:12.771 Eating properly, 0:03:12.771,0:03:15.006 is another great way [br]to increase dopamine. 0:03:15.006,0:03:17.510 Specifically, [br]eating fruits rich in tyrosine, 0:03:17.510,0:03:19.765 which is a precursor to dopamine, 0:03:19.765,0:03:22.748 will help, increase the available [br]dopamine in the brain. 0:03:22.748,0:03:24.235 Fruits rich in tyrosine 0:03:24.235,0:03:26.243 include things such as: Avocados, 0:03:26.243,0:03:28.275 almonds and bananas. 0:03:29.495,0:03:31.508 Another great way [br]to release dopamine, 0:03:31.508,0:03:33.501 is doing something [br]rewarding to you. 0:03:33.501,0:03:34.736 This can be a something 0:03:34.736,0:03:37.079 as easy as checking something [br]of your to do list, 0:03:37.079,0:03:40.232 or perhaps volunteering[br]on a community center. 0:03:40.232,0:03:41.742 And of course, 0:03:41.742,0:03:44.746 one of my personal favorite ways,[br]to increase dopamine, 0:03:44.746,0:03:47.172 is sex.[br](Laughter) 0:03:48.498,0:03:52.026 Sex release as many beneficial[br]chemicals in the brain 0:03:52.026,0:03:53.501 in addition to dopamine, 0:03:53.501,0:03:54.749 such as oxytocin, 0:03:54.749,0:03:57.247 which is implicated [br]in human bonding. 0:03:57.247,0:03:58.248 Serotonin, 0:03:58.248,0:04:01.248 which relates to happiness[br]and a feeling of well-being. 0:04:01.738,0:04:03.261 And norepinephrine, 0:04:03.261,0:04:04.774 which increase our alertness. 0:04:04.774,0:04:07.532 So how can we use[br]these information? 0:04:07.532,0:04:09.768 Professors can develop [br]new and exciting ways, 0:04:09.768,0:04:12.267 to deliver information to students. 0:04:12.267,0:04:14.247 It doesn't have [br]to be as exciting 0:04:14.247,0:04:15.770 as involving flames and explosion 0:04:15.770,0:04:18.230 like my chemistry professor. 0:04:18.230,0:04:19.750 It can be as simple as[br] 0:04:19.750,0:04:21.768 having students [br]do a hands-on experience, 0:04:21.768,0:04:25.256 or perhaps using[br]the students as props 0:04:25.256,0:04:27.501 to explain a difficult concept. 0:04:27.501,0:04:30.745 Professors, get away[br]from the traditional monologue lectures.[br] 0:04:30.745,0:04:32.773 It'll be more rewarding[br]for the professors, 0:04:32.773,0:04:36.241 and will stimulate the students[br]to promote long-term learning. 0:04:36.241,0:04:39.233 Let's get[br]those dopamine neurons firing. 0:04:39.233,0:04:41.520 Thank you.[br](Applause)