0:00:07.542,0:00:09.632 Every chicken was once an egg, 0:00:09.632,0:00:11.575 every oak tree an acorn, 0:00:11.575,0:00:13.573 every frog a tadpole. 0:00:13.573,0:00:15.283 The patch of mold on that old piece of bread 0:00:15.283,0:00:16.735 in the back of your fridge, 0:00:16.735,0:00:19.781 not so long ago that was one, solitary cell. 0:00:19.781,0:00:21.569 Even you were once but a gleam 0:00:21.569,0:00:23.742 in your parents' eyes. 0:00:24.818,0:00:26.346 All these organisms share 0:00:26.346,0:00:27.974 the same basic goal: 0:00:27.974,0:00:30.633 to perpetuate their own existence. 0:00:31.448,0:00:33.969 All lifeforms that we've discovered so far 0:00:33.969,0:00:35.178 stay alive by using 0:00:35.178,0:00:38.725 basically the same rules, materials, and machinery. 0:00:38.725,0:00:41.940 Imagine a factory full of robots. 0:00:41.940,0:00:43.028 These robots have two missions: 0:00:43.028,0:00:44.572 one, keep the factory running, 0:00:44.572,0:00:45.927 and two, when the time is right, 0:00:45.927,0:00:48.484 set up an entirely new factory. 0:00:49.114,0:00:49.783 To do those things, 0:00:49.783,0:00:51.755 they need assembly instructions, 0:00:51.755,0:00:52.862 raw materials, 0:00:52.862,0:00:54.029 plenty of energy, 0:00:54.029,0:00:56.003 a few rules about when to work normally, 0:00:56.003,0:00:57.011 when to work quickly, 0:00:57.011,0:00:58.037 or when to stop, 0:00:58.037,0:00:59.627 and some exchange currencies 0:00:59.627,0:01:02.587 because even robots need to get paid. 0:01:02.587,0:01:05.292 Each factory has a high security office with blueprints 0:01:05.292,0:01:08.260 for all the possible factory configurations 0:01:08.260,0:01:09.641 and complete sets of instructions 0:01:09.641,0:01:11.510 to make all the different types of robots 0:01:11.510,0:01:13.793 a factory could ever need. 0:01:13.793,0:01:15.971 Special robots photocopy these instructions 0:01:15.971,0:01:16.843 and send them off 0:01:16.843,0:01:19.469 to help make the building blocks of more robots. 0:01:19.469,0:01:21.093 Their colleagues assemble those parts 0:01:21.093,0:01:23.428 into still more robots, 0:01:23.428,0:01:24.256 which are transported 0:01:24.256,0:01:25.839 to the right location in the factory 0:01:25.839,0:01:28.894 and given the tools they need to start working. 0:01:28.894,0:01:30.261 Every robot draws energy 0:01:30.261,0:01:32.148 from the central power plant, 0:01:32.148,0:01:34.691 a giant furnace that can burn regular fuel 0:01:34.691,0:01:36.057 but also scrap materials 0:01:36.057,0:01:38.911 if not enough regular fuel is available. 0:01:39.895,0:01:41.212 Certain zones in the factory 0:01:41.212,0:01:42.794 have harsher working conditions, 0:01:42.794,0:01:44.623 so these areas are walled off. 0:01:44.623,0:01:46.875 But the robots inside can at least communicate 0:01:46.875,0:01:48.045 with the rest of the factory 0:01:48.045,0:01:49.454 through specialized portals 0:01:49.454,0:01:51.464 embedded directly into the walls. 0:01:52.433,0:01:53.723 And as you've probably figured out, 0:01:53.723,0:01:55.141 what we're describing here 0:01:55.141,0:01:56.429 is a cell. 0:01:56.429,0:01:59.035 The high security office is the nucleus. 0:01:59.035,0:02:00.392 It stores the blueprints and instructions 0:02:00.392,0:02:03.515 as deoxyribonucleic acid, or DNA. 0:02:03.515,0:02:06.226 The photocopied instructions are RNA. 0:02:06.226,0:02:08.437 The robots themselves are mostly proteins 0:02:08.437,0:02:09.852 built from amino acids, 0:02:09.852,0:02:11.409 but they'll often use special tools 0:02:11.409,0:02:13.227 that are, or are derived from, 0:02:13.227,0:02:15.045 vitamins and minerals. 0:02:15.045,0:02:16.863 The walls between factory zones 0:02:16.863,0:02:18.333 and around the factory itself 0:02:18.333,0:02:20.040 are mostly made up of lipids, 0:02:20.040,0:02:22.084 a.k.a. fats. 0:02:22.084,0:02:23.374 In most organisms, 0:02:23.374,0:02:25.455 the primary fuel source are sugars, 0:02:25.455,0:02:26.285 but in a pinch, 0:02:26.285,0:02:27.954 fats and proteins can be broken down 0:02:27.954,0:02:30.266 and burned in the furnace as well. 0:02:30.266,0:02:32.349 The portals are membrane proteins 0:02:32.349,0:02:34.847 which allow very specific materials and information 0:02:34.847,0:02:37.789 to pass through the walls at the right times. 0:02:37.789,0:02:39.555 Many interactions between robot proteins 0:02:39.555,0:02:41.677 require some kind of push, 0:02:41.677,0:02:43.923 think robot minimum wage. 0:02:43.923,0:02:46.193 A few small but crucial forms of money 0:02:46.193,0:02:47.983 are transferred between proteins 0:02:47.983,0:02:49.811 to provide this push. 0:02:49.811,0:02:52.939 Electrons, protons, oxygen, and phosphate groups 0:02:52.939,0:02:54.486 are the main chemical currencies, 0:02:54.486,0:02:56.612 and they're kept in small molecular wallets 0:02:56.612,0:02:59.518 or larger tote bags to keep them safe. 0:02:59.979,0:03:01.783 This is biochemistry, 0:03:01.783,0:03:03.740 the study of how every part of the factory 0:03:03.740,0:03:06.242 interacts to keep your life running smoothly 0:03:06.242,0:03:08.822 in the face of extreme challenges. 0:03:08.822,0:03:10.330 Maybe there's too much fuel; 0:03:10.330,0:03:13.510 your body will store the excess as glycogen or fat. 0:03:13.510,0:03:14.615 Maybe there's not enough; 0:03:14.615,0:03:17.122 your body will use up those energy reserves. 0:03:17.122,0:03:19.590 Maybe a virus or bacteria tries to invade; 0:03:19.590,0:03:22.138 your body will mobilize the immune system. 0:03:22.138,0:03:24.122 Maybe you touched something hot or sharp; 0:03:24.122,0:03:26.967 your nerves will let you know so you can stop. 0:03:26.967,0:03:29.687 Maybe it's time to create a new cell 0:03:29.687,0:03:31.242 or a new person. 0:03:31.843,0:03:34.569 Amazingly, oak trees, chickens, frogs, 0:03:34.569,0:03:36.102 and, yes, even you 0:03:36.102,0:03:37.646 share so many of the same 0:03:37.646,0:03:39.894 basic robot and factory designs 0:03:39.894,0:03:41.641 that biochemists can learn a lot 0:03:41.641,0:03:42.911 about all of them 0:03:42.911,0:03:45.202 all at the same time.