WEBVTT 00:00:08.085 --> 00:00:11.276 For the microscopic lab worm, C. elegans 00:00:11.276 --> 00:00:15.185 life equates to just a few short weeks on Earth. 00:00:15.185 --> 00:00:20.051 Compare that with the tortoise, which can age to more than 100 years. 00:00:20.051 --> 00:00:24.415 Mice and rats reach the end of their lives after just four years, 00:00:24.415 --> 00:00:28.141 while for the bowhead whale, Earth's longest-lived mammal, 00:00:28.141 --> 00:00:31.639 death can come after 200. 00:00:31.639 --> 00:00:33.190 Like most living things, 00:00:33.190 --> 00:00:38.420 the vast majority of animals gradually degenerate after reaching sexual maturity 00:00:38.420 --> 00:00:41.327 in the process known as aging. 00:00:41.327 --> 00:00:44.176 But what does it really mean to age? 00:00:44.176 --> 00:00:48.036 The drivers behind this process are varied and complicated, 00:00:48.036 --> 00:00:52.930 but aging is ultimately caused by cell death and dysfunction. 00:00:52.930 --> 00:00:55.707 When we're young, we constantly regenerate cells 00:00:55.707 --> 00:00:59.067 in order to replace dead and dying ones. 00:00:59.067 --> 00:01:01.835 But as we age, this process slows down. 00:01:01.835 --> 00:01:07.277 In addition, older cells don't perform their functions as well as young ones. 00:01:07.277 --> 00:01:09.666 That makes our bodies go into a decline, 00:01:09.666 --> 00:01:12.967 which eventually results in disease and death. 00:01:12.967 --> 00:01:15.637 But if that's consistently true, 00:01:15.637 --> 00:01:21.288 why the huge variance in aging patterns and lifespan within the animal kingdom? 00:01:21.288 --> 00:01:23.607 The answer lies in several factors, 00:01:23.607 --> 00:01:24.937 including environment 00:01:24.937 --> 00:01:27.187 and body size. 00:01:27.187 --> 00:01:31.368 These can place powerful evolutionary pressures on animals to adapt, 00:01:31.368 --> 00:01:36.158 which in turn makes the aging process different across species. 00:01:36.158 --> 00:01:39.959 Consider the cold depths of the Atlantic and Arctic Seas, 00:01:39.959 --> 00:01:43.328 where Greenland sharks can live to over 400 years, 00:01:43.328 --> 00:01:48.488 and the Arctic clam known as the quahog can live up to 500. 00:01:48.488 --> 00:01:51.429 Perhaps the most impressive of these ocean-dwelling ancients 00:01:51.429 --> 00:01:54.047 is the Antarctic glass sponge, 00:01:54.047 --> 00:01:58.388 which can survive over 10,000 years in frigid waters. 00:01:58.388 --> 00:02:03.828 In cold environments like these, heartbeats and metabolic rates slow down. 00:02:03.828 --> 00:02:08.769 Researchers theorize that this also causes a slowing of the aging process. 00:02:08.769 --> 00:02:13.159 In this way, the environment shapes longevity. 00:02:13.159 --> 00:02:15.799 When it comes to size, it's often, but not always, 00:02:15.799 --> 00:02:21.159 the case that larger species have a longer lifespan than smaller ones. 00:02:21.159 --> 00:02:24.199 For instance, an elephant or whale will live much longer 00:02:24.199 --> 00:02:26.498 than a mouse, rat, or vole, 00:02:26.498 --> 00:02:31.430 which in turn have years on flies and worms. 00:02:31.430 --> 00:02:33.820 Some small animals, like worms and flies, 00:02:33.820 --> 00:02:37.650 are also limited by the mechanics of their cell division. 00:02:37.650 --> 00:02:42.061 They're mostly made up of cells that can't divide and be replaced when damaged, 00:02:42.061 --> 00:02:45.090 so their bodies expire more quickly. 00:02:45.090 --> 00:02:49.180 And size is a powerful evolutionary driver in animals. 00:02:49.180 --> 00:02:52.020 Smaller creatures are more prone to predators. 00:02:52.020 --> 00:02:56.961 A mouse, for instance, can hardly expect to survive more than a year in the wild. 00:02:56.961 --> 00:03:00.810 So, it has evolved to grow and reproduce more rapidly, 00:03:00.810 --> 00:03:05.551 like an evolutionary defense mechanism against its shorter lifespan. 00:03:05.551 --> 00:03:09.520 Larger animals, by contrast, are better at fending off predators, 00:03:09.520 --> 00:03:12.901 and so they have the luxury of time to grow to large sizes 00:03:12.901 --> 00:03:16.232 and reproduce multiple times during their lives. 00:03:16.232 --> 00:03:22.672 Exceptions to the size rule include bats, birds, moles, and turtles, 00:03:22.672 --> 00:03:25.537 but in each case, these animals have other adaptations 00:03:25.537 --> 00:03:29.231 that allow them to escape predators. 00:03:29.231 --> 00:03:32.771 But there are still cases where animals with similar defining features, 00:03:32.771 --> 00:03:34.791 like size and habitat, 00:03:34.791 --> 00:03:37.791 age at completely different rates. 00:03:37.791 --> 00:03:39.891 In these cases, genetic differences, 00:03:39.891 --> 00:03:43.261 like how each organism's cells respond to threats, 00:03:43.261 --> 00:03:47.553 often account for the discrepancies in longevity. 00:03:47.553 --> 00:03:49.902 So it's the combination of all these factors 00:03:49.902 --> 00:03:52.912 playing out to differing degrees in different animals 00:03:52.912 --> 00:03:57.733 that explains the variability we see in the animal kingdom. 00:03:57.733 --> 00:03:59.703 So what about us? 00:03:59.703 --> 00:04:03.772 Humans currently have an average life expectancy of 71 years, 00:04:03.772 --> 00:04:08.862 meaning that we're not even close to being the longest living inhabitants on Earth. 00:04:08.862 --> 00:04:13.041 But we are very good at increasing our life expectancy. 00:04:13.041 --> 00:04:17.898 In the early 1900s, humans only lived an average of 50 years. 00:04:17.898 --> 00:04:21.712 Since then, we've learned to adapt by managing many of the factors 00:04:21.712 --> 00:04:23.072 that cause deaths, 00:04:23.072 --> 00:04:26.403 like environmental exposure and nutrition. 00:04:26.403 --> 00:04:29.053 This, and other increases in life expectancy 00:04:29.053 --> 00:04:32.033 make us possibly the only species on Earth 00:04:32.033 --> 00:04:35.093 to take control over our natural fate.