WEBVTT 00:00:02.760 --> 00:00:04.280 Here's a question that matters. NOTE Paragraph 00:00:04.880 --> 00:00:06.856 [Is it ethical to evolve the human body?] NOTE Paragraph 00:00:06.880 --> 00:00:10.376 Because we're beginning to get all the tools together to evolve ourselves. 00:00:10.400 --> 00:00:12.816 And we can evolve bacteria and we can evolve plants 00:00:12.840 --> 00:00:14.256 and we can evolve animals, 00:00:14.280 --> 00:00:17.096 and we're now reaching a point where we really have to ask, 00:00:17.120 --> 00:00:19.960 is it really ethical and do we want to evolve human beings? 00:00:21.440 --> 00:00:23.336 And as you're thinking about that, 00:00:23.360 --> 00:00:27.096 let me talk about that in the context of prosthetics, 00:00:27.120 --> 00:00:29.800 prosthetics past, present, future. NOTE Paragraph 00:00:30.920 --> 00:00:32.496 So this is the iron hand 00:00:32.520 --> 00:00:34.856 that belonged to one of the German counts. 00:00:34.880 --> 00:00:39.296 Loved to fight, lost his arm in one of these battles. 00:00:39.320 --> 00:00:41.776 No problem, he just made a suit of armor, 00:00:41.800 --> 00:00:43.136 put it on, 00:00:43.160 --> 00:00:44.416 perfect prosthetic. 00:00:44.440 --> 00:00:48.360 That's where the concept of ruling with an iron fist comes from. NOTE Paragraph 00:00:49.600 --> 00:00:53.056 And of course these prosthetics have been getting more and more useful, 00:00:53.080 --> 00:00:54.336 more and more modern. 00:00:54.360 --> 00:00:56.816 You can hold soft-boiled eggs. 00:00:56.840 --> 00:01:00.336 You can have all types of controls, and as you're thinking about that, 00:01:00.360 --> 00:01:02.376 there are wonderful people like Hugh Herr 00:01:02.400 --> 00:01:05.239 who have been building absolutely extraordinary prosthetics. 00:01:05.720 --> 00:01:08.536 So the wonderful Aimee Mullins will go out and say, 00:01:08.560 --> 00:01:10.240 how tall do I want to be tonight? 00:01:11.040 --> 00:01:13.936 Or Hugh will say what type of cliff do I want to climb? 00:01:13.960 --> 00:01:18.456 Or does somebody want to run a marathon, or does somebody want to ballroom dance? 00:01:18.480 --> 00:01:20.456 And as you adapt these things, 00:01:20.480 --> 00:01:24.616 the interesting thing about prosthetics is they've been coming inside the body. 00:01:24.640 --> 00:01:27.616 So these external prosthetics have now become artificial knees. 00:01:27.640 --> 00:01:29.696 They've become artificial hips. 00:01:29.720 --> 00:01:31.936 And then they've evolved further 00:01:31.960 --> 00:01:33.976 to become not just nice to have 00:01:34.000 --> 00:01:35.200 but essential to have. NOTE Paragraph 00:01:35.920 --> 00:01:39.776 So when you're talking about a heart pacemaker as a prosthetic, 00:01:39.800 --> 00:01:43.496 you're talking about something that isn't just, "I'm missing my leg," 00:01:43.520 --> 00:01:45.936 it's, "if I don't have this, I can die." 00:01:45.960 --> 00:01:50.056 And at that point, a prosthetic becomes a symbiotic relationship 00:01:50.080 --> 00:01:51.280 with the human body. NOTE Paragraph 00:01:52.560 --> 00:01:55.096 And four of the smartest people that I've ever met -- 00:01:55.120 --> 00:02:00.376 Ed Boyden, Hugh Herr, Joe Jacobson, Bob Lander -- 00:02:00.400 --> 00:02:02.976 are working on a Center for Extreme Bionics. 00:02:03.000 --> 00:02:05.616 And the interesting thing of what you're seeing here is 00:02:05.640 --> 00:02:08.056 these prosthetics now get integrated into the bone. 00:02:08.080 --> 00:02:09.735 They get integrated into the skin. 00:02:09.759 --> 00:02:11.475 They get integrated into the muscle. 00:02:12.360 --> 00:02:15.336 And one of the other sides of Ed 00:02:15.360 --> 00:02:18.256 is he's been thinking about how to connect the brain 00:02:18.280 --> 00:02:20.976 using light or other mechanisms 00:02:21.000 --> 00:02:23.280 directly to things like these prosthetics. 00:02:24.520 --> 00:02:25.776 And if you can do that, 00:02:25.800 --> 00:02:29.000 then you can begin changing fundamental aspects of humanity. 00:02:29.840 --> 00:02:33.840 So how quickly you react to something depends on the diameter of a nerve. 00:02:34.920 --> 00:02:38.800 And of course, if you have nerves that are external or prosthetic, 00:02:39.600 --> 00:02:41.480 say with light or liquid metal, 00:02:42.280 --> 00:02:43.976 then you can increase that diameter 00:02:44.000 --> 00:02:47.056 and you could even increase it theoretically to the point where, 00:02:47.080 --> 00:02:51.120 as long as you could see the muzzle flash, you could step out of the way of a bullet. 00:02:51.840 --> 00:02:54.960 Those are the order of magnitude of changes you're talking about. NOTE Paragraph 00:02:56.200 --> 00:02:58.776 This is a fourth sort of level of prosthetics. 00:02:58.800 --> 00:03:01.336 These are Phonak hearing aids, 00:03:01.360 --> 00:03:03.416 and the reason why these are so interesting 00:03:03.440 --> 00:03:06.856 is because they cross the threshold from where prosthetics are something 00:03:06.880 --> 00:03:08.309 for somebody who is "disabled" 00:03:09.560 --> 00:03:13.616 and they become something that somebody who is "normal" 00:03:13.640 --> 00:03:15.536 might want to actually have, 00:03:15.560 --> 00:03:18.536 because what this prosthetic does, which is really interesting, 00:03:18.560 --> 00:03:20.216 is not only does it help you hear, 00:03:20.240 --> 00:03:21.576 you can focus your hearing, 00:03:21.600 --> 00:03:24.056 so it can hear the conversation going on over there. 00:03:24.080 --> 00:03:25.336 You can have superhearing. 00:03:25.360 --> 00:03:28.296 You can have hearing in 360 degrees. You can have white noise. 00:03:28.320 --> 00:03:31.520 You can record, and oh, by the way, they also put a phone into this. 00:03:32.440 --> 00:03:35.320 So this functions as your hearing aid and also as your phone. 00:03:35.920 --> 00:03:41.080 And at that point, somebody might actually want to have a prosthetic voluntarily. NOTE Paragraph 00:03:42.400 --> 00:03:45.096 All of these thousands of loosely connected little pieces 00:03:45.120 --> 00:03:46.320 are coming together, 00:03:47.120 --> 00:03:49.056 and it's about time we ask the question, 00:03:49.080 --> 00:03:52.240 how do we want to evolve human beings over the next century or two? 00:03:53.640 --> 00:03:55.680 And for that we turn to a great philosopher 00:03:56.920 --> 00:03:59.976 who was a very smart man despite being a Yankee fan. NOTE Paragraph 00:04:00.000 --> 00:04:01.880 (Laughter) NOTE Paragraph 00:04:02.800 --> 00:04:06.616 And Yogi Berra used to say, of course, that it's very tough to make predictions, 00:04:06.640 --> 00:04:08.016 especially about the future. NOTE Paragraph 00:04:08.040 --> 00:04:09.136 (Laughter) NOTE Paragraph 00:04:09.160 --> 00:04:12.216 So instead of making a prediction about the future to begin with, 00:04:12.240 --> 00:04:15.576 let's take what's happening in the present with people like Tony Atala, 00:04:15.600 --> 00:04:17.839 who is redesigning 30-some-odd organs. 00:04:19.200 --> 00:04:22.776 And maybe the ultimate prosthetic isn't having something external, titanium. 00:04:22.800 --> 00:04:25.496 Maybe the ultimate prosthetic is take your own gene code, 00:04:25.520 --> 00:04:26.840 remake your own body parts, 00:04:27.920 --> 00:04:31.520 because that's a whole lot more effective than any kind of a prosthetic. 00:04:32.440 --> 00:04:36.456 But while you're at it, then you can take the work of Craig Venter and Ham Smith. 00:04:36.480 --> 00:04:38.536 And one of the things that we've been doing 00:04:38.560 --> 00:04:41.120 is trying to figure out how to reprogram cells. 00:04:42.280 --> 00:04:43.856 And if you can reprogram a cell, 00:04:43.880 --> 00:04:46.120 then you can change the cells in those organs. 00:04:47.400 --> 00:04:49.616 So if you can change the cells in those organs, 00:04:49.640 --> 00:04:52.136 maybe you make those organs more radiation-resistant. 00:04:52.160 --> 00:04:54.056 Maybe you make them absorb more oxygen. 00:04:54.080 --> 00:04:55.736 Maybe you make them more efficient 00:04:55.760 --> 00:04:58.240 to filter out stuff that you don't want in your body. NOTE Paragraph 00:04:59.440 --> 00:05:03.096 And over the last few weeks, George Church has been in the news a lot 00:05:03.120 --> 00:05:06.416 because he's been talking about taking one of these programmable cells 00:05:06.440 --> 00:05:08.176 and inserting an entire human genome 00:05:08.200 --> 00:05:09.400 into that cell. 00:05:10.480 --> 00:05:14.296 And once you can insert an entire human genome into a cell, 00:05:14.320 --> 00:05:16.456 then you begin to ask the question, 00:05:16.480 --> 00:05:19.160 would you want to enhance any of that genome? 00:05:21.440 --> 00:05:23.776 Do you want to enhance a human body? 00:05:23.800 --> 00:05:26.096 How would you want to enhance a human body? 00:05:26.120 --> 00:05:28.216 Where is it ethical to enhance a human body 00:05:28.240 --> 00:05:31.496 and where is it not ethical to enhance a human body? 00:05:31.520 --> 00:05:33.416 And all of a sudden, what we're doing 00:05:33.440 --> 00:05:36.376 is we've got this multidimensional chess board 00:05:36.400 --> 00:05:39.656 where we can change human genetics by using viruses 00:05:39.680 --> 00:05:41.120 to attack things like AIDS, 00:05:42.120 --> 00:05:44.536 or we can change the gene code through gene therapy 00:05:44.560 --> 00:05:47.496 to do away with some hereditary diseases, 00:05:47.520 --> 00:05:49.136 or we can change the environment, 00:05:49.160 --> 00:05:51.827 and change the expression of those genes in the epigenome 00:05:51.851 --> 00:05:53.811 and pass that on to the next generations. 00:05:55.320 --> 00:05:58.456 And all of a sudden, it's not just one little bit, 00:05:58.480 --> 00:06:00.336 it's all these stacked little bits 00:06:00.360 --> 00:06:02.440 that allow you to take little portions of it 00:06:03.280 --> 00:06:05.280 until all the portions coming together 00:06:06.160 --> 00:06:08.240 lead you to something that's very different. NOTE Paragraph 00:06:09.600 --> 00:06:12.336 And a lot of people are very scared by this stuff. 00:06:12.360 --> 00:06:15.280 And it does sound scary, and there are risks to this stuff. 00:06:16.040 --> 00:06:18.736 So why in the world would you ever want to do this stuff? 00:06:18.760 --> 00:06:21.776 Why would we really want to alter the human body 00:06:21.800 --> 00:06:23.000 in a fundamental way? NOTE Paragraph 00:06:25.040 --> 00:06:27.336 The answer lies in part 00:06:27.360 --> 00:06:28.560 with Lord Rees, 00:06:29.240 --> 00:06:30.920 astronomer royal of Great Britain. 00:06:32.560 --> 00:06:36.376 And one of his favorite sayings is the universe is 100 percent malevolent. 00:06:36.400 --> 00:06:37.616 So what does that mean? 00:06:37.640 --> 00:06:40.536 It means if you take any one of your bodies at random, 00:06:40.560 --> 00:06:42.456 drop it anywhere in the universe, 00:06:42.480 --> 00:06:44.200 drop it in space, you die. 00:06:44.720 --> 00:06:46.096 Drop it on the Sun, you die. 00:06:46.120 --> 00:06:48.136 Drop it on the surface of Mercury, you die. 00:06:48.160 --> 00:06:49.800 Drop it near a supernova, you die. 00:06:50.240 --> 00:06:53.360 But fortunately, it's only about 80 percent effective. NOTE Paragraph 00:06:54.640 --> 00:06:56.680 So as a great physicist once said, 00:06:58.000 --> 00:07:02.136 there's these little upstream eddies of biology 00:07:02.160 --> 00:07:06.800 that create order in this rapid torrent of entropy. 00:07:08.080 --> 00:07:11.056 So as the universe dissipates energy, 00:07:11.080 --> 00:07:14.560 there's these upstream eddies that create biological order. 00:07:15.960 --> 00:07:18.376 Now, the problem with eddies is, 00:07:18.400 --> 00:07:19.896 they tend to disappear. 00:07:19.920 --> 00:07:21.800 They shift. They move in rivers. 00:07:22.680 --> 00:07:24.656 And because of that, when an eddy shifts, 00:07:24.680 --> 00:07:28.216 when the Earth becomes a snowball, when the Earth becomes very hot, 00:07:28.240 --> 00:07:31.496 when the Earth gets hit by an asteroid, when you have supervolcanoes, 00:07:31.520 --> 00:07:33.376 when you have solar flares, 00:07:33.400 --> 00:07:36.736 when you have potentially extinction-level events 00:07:36.760 --> 00:07:37.976 like the next election -- NOTE Paragraph 00:07:38.000 --> 00:07:40.160 (Laughter) NOTE Paragraph 00:07:41.440 --> 00:07:44.680 then all of a sudden, you can have periodic extinctions. 00:07:45.400 --> 00:07:47.840 And by the way, that's happened five times on Earth, 00:07:48.360 --> 00:07:50.456 and therefore it is very likely 00:07:50.480 --> 00:07:53.520 that the human species on Earth is going to go extinct someday. 00:07:54.440 --> 00:07:55.936 Not next week, 00:07:55.960 --> 00:07:57.776 not next month, 00:07:57.800 --> 00:08:00.680 maybe in November, but maybe 10,000 years after that. 00:08:01.880 --> 00:08:04.696 As you're thinking of the consequence of that, 00:08:04.720 --> 00:08:08.136 if you believe that extinctions are common and natural 00:08:08.160 --> 00:08:10.456 and normal and occur periodically, 00:08:10.480 --> 00:08:13.360 it becomes a moral imperative to diversify our species. NOTE Paragraph 00:08:14.520 --> 00:08:16.136 And it becomes a moral imperative 00:08:16.160 --> 00:08:19.136 because it's going to be really hard to live on Mars 00:08:19.160 --> 00:08:21.880 if we don't fundamentally modify the human body. 00:08:22.880 --> 00:08:24.096 Right? 00:08:24.120 --> 00:08:25.456 You go from one cell, 00:08:25.480 --> 00:08:27.696 mom and dad coming together to make one cell, 00:08:27.720 --> 00:08:29.896 in a cascade to 10 trillion cells. 00:08:29.920 --> 00:08:34.376 We don't know, if you change the gravity substantially, 00:08:34.400 --> 00:08:36.880 if the same thing will happen to create your body. 00:08:38.159 --> 00:08:41.216 We do know that if you expose our bodies as they currently are 00:08:41.240 --> 00:08:43.360 to a lot of radiation, we will die. 00:08:45.040 --> 00:08:48.096 So as you're thinking of that, you have to really redesign things 00:08:48.120 --> 00:08:49.376 just to get to Mars. 00:08:49.400 --> 00:08:52.320 Forget about the moons of Neptune or Jupiter. NOTE Paragraph 00:08:53.000 --> 00:08:55.456 And to borrow from Nikolai Kardashev, 00:08:55.480 --> 00:08:57.656 let's think about life in a series of scales. 00:08:57.680 --> 00:09:00.176 So Life One civilization 00:09:00.200 --> 00:09:03.200 is a civilization that begins to alter his or her looks. 00:09:04.080 --> 00:09:06.376 And we've been doing that for thousands of years. 00:09:06.400 --> 00:09:09.560 You've got tummy tucks and you've got this and you've got that. 00:09:10.280 --> 00:09:12.696 You alter your looks, and I'm told 00:09:12.720 --> 00:09:16.040 that not all of those alterations take place for medical reasons. NOTE Paragraph 00:09:16.680 --> 00:09:18.736 (Laughter) NOTE Paragraph 00:09:18.760 --> 00:09:19.960 Seems odd. NOTE Paragraph 00:09:20.360 --> 00:09:22.880 A Life Two civilization is a different civilization. 00:09:24.320 --> 00:09:28.880 A Life Two civilization alters fundamental aspects of the body. 00:09:29.840 --> 00:09:32.696 So you put human growth hormone in, the person grows taller, 00:09:32.720 --> 00:09:36.656 or you put x in and the person gets fatter or loses metabolism 00:09:36.680 --> 00:09:38.296 or does a whole series of things, 00:09:38.320 --> 00:09:41.016 but you're altering the functions in a fundamental way. NOTE Paragraph 00:09:41.040 --> 00:09:43.656 To become an intrasolar civilization, 00:09:43.680 --> 00:09:46.400 we're going to have to create a Life Three civilization, 00:09:47.720 --> 00:09:50.320 and that looks very different from what we've got here. 00:09:50.840 --> 00:09:53.056 Maybe you splice in Deinococcus radiodurans 00:09:53.080 --> 00:09:57.200 so that the cells can resplice after a lot of exposure to radiation. 00:09:58.320 --> 00:10:01.336 Maybe you breathe by having oxygen flow through your blood 00:10:01.360 --> 00:10:02.800 instead of through your lungs. 00:10:03.600 --> 00:10:06.320 But you're talking about really radical redesigns, 00:10:07.480 --> 00:10:10.696 and one of the interesting things that's happened in the last decade 00:10:10.720 --> 00:10:13.456 is we've discovered a whole lot of planets out there. 00:10:13.480 --> 00:10:15.160 And some of them may be Earth-like. 00:10:17.440 --> 00:10:21.056 The problem is, if we ever want to get to these planets, 00:10:21.080 --> 00:10:22.736 the fastest human objects -- 00:10:22.760 --> 00:10:25.336 Juno and Voyager and the rest of this stuff -- 00:10:25.360 --> 00:10:27.856 take tens of thousands of years 00:10:27.880 --> 00:10:30.000 to get from here to the nearest solar system. 00:10:30.720 --> 00:10:33.680 So if you want to start exploring beaches somewhere else, 00:10:34.400 --> 00:10:36.800 or you want to see two-sun sunsets, 00:10:37.840 --> 00:10:40.976 then you're talking about something that is very different, 00:10:41.000 --> 00:10:46.056 because you have to change the timescale and the body of humans 00:10:46.080 --> 00:10:49.000 in ways which may be absolutely unrecognizable. 00:10:50.000 --> 00:10:51.840 And that's a Life Four civilization. NOTE Paragraph 00:10:53.720 --> 00:10:56.656 Now, we can't even begin to imagine what that might look like, 00:10:56.680 --> 00:10:59.016 but we're beginning to get glimpses 00:10:59.040 --> 00:11:02.400 of instruments that might take us even that far. 00:11:02.960 --> 00:11:04.576 And let me give you two examples. NOTE Paragraph 00:11:04.600 --> 00:11:06.553 So this is the wonderful Floyd Romesberg, 00:11:07.200 --> 00:11:09.336 and one of the things that Floyd's been doing 00:11:09.360 --> 00:11:11.896 is he's been playing with the basic chemistry of life. 00:11:11.920 --> 00:11:16.776 So all life on this planet is made in ATCGs, the four letters of DNA. 00:11:16.800 --> 00:11:19.936 All bacteria, all plants, all animals, all humans, all cows, 00:11:19.960 --> 00:11:21.160 everything else. 00:11:22.440 --> 00:11:26.616 And what Floyd did is he changed out two of those base pairs, 00:11:26.640 --> 00:11:28.160 so it's ATXY. 00:11:29.760 --> 00:11:35.456 And that means that you now have a parallel system to make life, 00:11:35.480 --> 00:11:39.776 to make babies, to reproduce, to evolve, 00:11:39.800 --> 00:11:41.976 that doesn't mate with most things on Earth 00:11:42.000 --> 00:11:43.880 or in fact maybe with nothing on Earth. 00:11:44.880 --> 00:11:47.416 Maybe you make plants that are immune to all bacteria. 00:11:47.440 --> 00:11:49.936 Maybe you make plants that are immune to all viruses. 00:11:49.960 --> 00:11:51.496 But why is that so interesting? 00:11:51.520 --> 00:11:54.680 It means that we are not a unique solution. 00:11:55.400 --> 00:11:59.136 It means you can create alternate chemistries to us 00:11:59.160 --> 00:12:03.976 that could be chemistries adaptable to a very different planet 00:12:04.000 --> 00:12:06.360 that could create life and heredity. NOTE Paragraph 00:12:08.120 --> 00:12:09.360 The second experiment, 00:12:10.480 --> 00:12:12.560 or the other implication of this experiment, 00:12:13.360 --> 00:12:17.576 is that all of you, all life is based on 20 amino acids. 00:12:17.600 --> 00:12:20.056 If you don't substitute two amino acids, 00:12:20.080 --> 00:12:25.656 if you don't say ATXY, if you say ATCG + XY, 00:12:25.680 --> 00:12:28.440 then you go from 20 building blocks to 172, 00:12:29.520 --> 00:12:32.656 and all of a sudden you've got 172 building blocks of amino acids 00:12:32.680 --> 00:12:35.480 to build life-forms in very different shapes. NOTE Paragraph 00:12:37.480 --> 00:12:40.536 The second experiment to think about is a really weird experiment 00:12:40.560 --> 00:12:42.640 that's been taking place in China. 00:12:43.920 --> 00:12:47.960 So this guy has been transplanting hundreds of mouse heads. 00:12:48.920 --> 00:12:50.296 Right? 00:12:50.320 --> 00:12:52.400 And why is that an interesting experiment? 00:12:53.440 --> 00:12:55.496 Well, think of the first heart transplants. 00:12:55.520 --> 00:12:57.136 One of the things they used to do 00:12:57.160 --> 00:13:00.696 is they used to bring in the wife or the daughter of the donor 00:13:00.720 --> 00:13:04.616 so the donee could tell the doctors, 00:13:04.640 --> 00:13:07.256 "Do you recognize this person? Do you love this person? 00:13:07.280 --> 00:13:09.136 Do you feel anything for this person?" 00:13:09.160 --> 00:13:10.640 We laugh about that today. 00:13:11.560 --> 00:13:13.776 We laugh because we know the heart is a muscle, 00:13:13.800 --> 00:13:17.296 but for hundreds of thousands of years, or tens of thousands of years, 00:13:17.320 --> 00:13:20.216 "I gave her my heart. She took my heart. She broke my heart." 00:13:20.240 --> 00:13:21.616 We thought this was emotion 00:13:21.640 --> 00:13:24.880 and we thought maybe emotions were transplanted with the heart. Nope. NOTE Paragraph 00:13:26.000 --> 00:13:27.480 So how about the brain? 00:13:29.040 --> 00:13:31.120 Two possible outcomes to this experiment. 00:13:31.880 --> 00:13:34.296 If you can get a mouse 00:13:34.320 --> 00:13:35.936 that is functional, 00:13:35.960 --> 00:13:37.160 then you can see, 00:13:38.040 --> 00:13:39.640 is the new brain a blank slate? 00:13:41.280 --> 00:13:43.320 And boy, does that have implications. 00:13:45.120 --> 00:13:46.320 Second option: 00:13:46.800 --> 00:13:48.920 the new mouse recognizes Minnie Mouse. 00:13:49.760 --> 00:13:51.856 The new mouse remembers what it's afraid of, 00:13:51.880 --> 00:13:53.576 remembers how to navigate the maze, 00:13:53.600 --> 00:13:54.800 and if that is true, 00:13:56.040 --> 00:13:59.360 then you can transplant memory and consciousness. 00:14:01.080 --> 00:14:03.496 And then the really interesting question is, 00:14:03.520 --> 00:14:07.456 if you can transplant this, is the only input-output mechanism 00:14:07.480 --> 00:14:08.680 this down here? 00:14:09.440 --> 00:14:12.136 Or could you transplant that consciousness into something 00:14:12.160 --> 00:14:14.136 that would be very different, 00:14:14.160 --> 00:14:15.416 that would last in space, 00:14:15.440 --> 00:14:17.496 that would last tens of thousands of years, 00:14:17.520 --> 00:14:19.520 that would be a completely redesigned body 00:14:19.544 --> 00:14:23.224 that could hold consciousness for a long, long period of time? NOTE Paragraph 00:14:26.040 --> 00:14:28.080 And let's come back to the first question: 00:14:28.560 --> 00:14:30.440 Why would you ever want to do that? 00:14:32.320 --> 00:14:33.576 Well, I'll tell you why. 00:14:33.600 --> 00:14:35.320 Because this is the ultimate selfie. NOTE Paragraph 00:14:36.000 --> 00:14:37.800 (Laughter) NOTE Paragraph 00:14:38.440 --> 00:14:41.000 This is taken from six billion miles away, 00:14:42.040 --> 00:14:43.240 and that's Earth. 00:14:44.800 --> 00:14:46.000 And that's all of us. 00:14:47.240 --> 00:14:50.760 And if that little thing goes, all of humanity goes. 00:14:52.320 --> 00:14:54.536 And the reason you want to alter the human body 00:14:54.560 --> 00:14:57.336 is because you eventually want a picture that says, 00:14:57.360 --> 00:14:59.296 that's us, and that's us, 00:14:59.320 --> 00:15:00.736 and that's us, 00:15:00.760 --> 00:15:03.880 because that's the way humanity survives long-term extinction. 00:15:05.440 --> 00:15:07.696 And that's the reason why it turns out 00:15:07.720 --> 00:15:11.656 it's actually unethical not to evolve the human body 00:15:11.680 --> 00:15:15.016 even though it can be scary, even though it can be challenging, 00:15:15.040 --> 00:15:18.416 but it's what's going to allow us to explore, live 00:15:18.440 --> 00:15:20.960 and get to places we can't even dream of today, 00:15:21.760 --> 00:15:25.496 but which our great-great-great-great- grandchildren might someday. NOTE Paragraph 00:15:25.520 --> 00:15:26.736 Thank you very much. NOTE Paragraph 00:15:26.760 --> 00:15:32.280 (Applause)