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When you talk about this problem to patients and the public

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but also doctors and policy makers

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They are appalled at what we've tolerated.

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We've had three decades of failing to fix this problem

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and the time really has come to draw a line underneath it

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and fix it for good.

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When I saw the doctor who gave me the diagnosis

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I wanted to hear anything but the word 'cancer'

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But that didn't happen.

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When, a couple of days later

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my doctor raised the possibility of a clinical trial

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there wasn't really much of a decision that I felt that I had to make.

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I genuinely wanted some good to come out of my situation

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no matter what was going to happen to me.

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To find out that not all clinical trials were being published

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is just horrifying - it's an insult to me

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and to everyone else who volunteers to do these trials.

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Doctors have unintentionally wasted huge amounts of money

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on treatments which either are less effective than we thought

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or were unnecessarily expensive

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and we've exposed patients to harm

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by giving them the less effective of the currently available treatment

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simply because clinical trial results have been withheld from us.

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The best currently available evidence shows that on average

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the chances of a completed trial being published are roughly 50/50.

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And trials with positive, flattering results

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are about twice as likely to be published as trials with negative results.

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The vast majority of medicines we use every day

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came on the market a decade or more ago.

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It's these trials where half of them haven't published results

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so for the medicines we use every day, information is missing.

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How can they possibly run trials on healthy volunteers

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or worse, on sick people

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knowing that they don't intend to make the information available?

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We need immediate access to the full methods and results

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of all trials on all uses of all the treatments

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that are currently being prescribed to millions of patients today.

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Hundreds of organisations who have joined the campaign

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including research funders, companies, and academic institutes

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have started serious discussions

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about all they can do to achieve more transparency.

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Terms like trust and transparency

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haven't been closely associated with the industry

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and at GSK we've realised there's more we can do

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to be more open and transparent about the research we conduct.

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And if independent researchers can come along

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and provide a fresh perspective on the research we've done

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that's great for science, it's great for us

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and most importantly it's going to improve patient care.

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Clinical trials aren't just done on drugs.

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They're done on psychiatric treatments, medical devices

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surgical techniques, and veterinary science.

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Anybody who funds and runs clinical trials should sign up to the campaign.

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Yes it's worrying about what you might find

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everybody has skeletons in their cupboards.

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But now is the time for more companies

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and more institutes to make a commitment.

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We know that withholding the results of clinical trials costs lives

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wastes money, inflicts avoidable suffering and harm on patients.

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And so I don't think it's any longer tenable to say "we didn't know".

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To make medicine better, we've got to make clinical trials count.

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Please share this film with friends and family and sign the petition at alltrials.net